PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19223576-6	2009	While dissecting the molecular events, both upstream and downstream of Akt, we found that psoralidin inhibits phosphatidylinositol 3-kinase activation and transcriptionally represses the activation of nuclear factor-kappaB and its target genes (Bcl-2, Survivin, and Bcl-xL, etc.	psoralidin	90-100	BCL2 apoptosis regulator	Homo sapiens	245-250	
27025925-5	2019	Psoralidin also increases the expression of pro-apoptosis genes Bax, Bid and p53 while decreases the expression of pro-survival genes Bcl-2 and Bcl-xL, both in a concentration dependent manner between 4 and 64 mumol/L (P<0.05 at 16 and 64 mumol/L).	psoralidin	0-10	BCL2 apoptosis regulator	Homo sapiens	134-139	
31786860-13	2019	DAPI staining revealed that Psoralidin triggered apoptotic cell death of HepG2 cells which was accompanied with activation of caspases 3 and 9, upregulation of Bax and downregulation of Bcl-2.	psoralidin	28-38	BCL2 apoptosis regulator	Homo sapiens	186-191	
26870201-0	2016	Differential effect of psoralidin in enhancing apoptosis of colon cancer cells via nuclear factor-kappaB and B-cell lymphoma-2/B-cell lymphoma-2-associated X protein signaling pathways.	psoralidin	23-33	BCL2 apoptosis regulator	Homo sapiens	109-126	
26870201-0	2016	Differential effect of psoralidin in enhancing apoptosis of colon cancer cells via nuclear factor-kappaB and B-cell lymphoma-2/B-cell lymphoma-2-associated X protein signaling pathways.	psoralidin	23-33	BCL2 apoptosis regulator	Homo sapiens	127-144	
26870201-12	2016	Furthermore, psoralidin was able to reduce Bcl-2 protein expression and increase Bax protein expression in SW480 cells.	psoralidin	13-23	BCL2 apoptosis regulator	Homo sapiens	43-48	
26870201-13	2016	Notably, Bcl-2 inhibitor was observed to enhance the effects of psoralidin on SW480 cells.	psoralidin	64-74	BCL2 apoptosis regulator	Homo sapiens	9-14	
26870201-14	2016	The results of the present study suggest that psoralidin may be a candidate drug for the treatment of colon cancer by inhibition of the NF-kappaB and Bcl-2/Bax signaling pathways.	psoralidin	46-56	BCL2 apoptosis regulator	Homo sapiens	150-155	
19851870-6	2010	Our results suggest that psoralidin inhibits constitutive and TNF-induced expression of TNF-alpha and its downstream prosurvival signaling molecules such as NF-kappaB and Bcl-2 in AIPC cells.	psoralidin	25-35	BCL2 apoptosis regulator	Homo sapiens	171-176