PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32249647-9 2020 Furthermore, laquinimod prevented the reduction of sirtuin 1 (SIRT1) from MPP+ stimulation. laquinimod 13-23 sirtuin 1 Homo sapiens 51-60 32249647-9 2020 Furthermore, laquinimod prevented the reduction of sirtuin 1 (SIRT1) from MPP+ stimulation. laquinimod 13-23 sirtuin 1 Homo sapiens 62-67 32249647-10 2020 Inhibition of SIRT1 abolished the protective effects of laquinimod against the activation of the NLRP3 inflammasome, suggesting the involvement of SIRT1 in this process.Conclusion: These findings suggest that laquinimod treatment might be a possible therapeutic strategy for neuroinflammation in PD. laquinimod 56-66 sirtuin 1 Homo sapiens 14-19 32249647-10 2020 Inhibition of SIRT1 abolished the protective effects of laquinimod against the activation of the NLRP3 inflammasome, suggesting the involvement of SIRT1 in this process.Conclusion: These findings suggest that laquinimod treatment might be a possible therapeutic strategy for neuroinflammation in PD. laquinimod 209-219 sirtuin 1 Homo sapiens 14-19 32249647-10 2020 Inhibition of SIRT1 abolished the protective effects of laquinimod against the activation of the NLRP3 inflammasome, suggesting the involvement of SIRT1 in this process.Conclusion: These findings suggest that laquinimod treatment might be a possible therapeutic strategy for neuroinflammation in PD. laquinimod 209-219 sirtuin 1 Homo sapiens 147-152