PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11390502-9	2001	Using either AG-490 or wortmannin alone, we observed a dose-dependent inhibition of GM-CSF-induced Mcl-1 expression.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	13-19	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	99-104	
11390502-10	2001	Using suboptimal doses of AG-490 and wortmannin, we found that both drugs together had an additive effect on delayed apoptosis and Mcl-1 expression.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	26-32	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	131-136	
26184999-0	2015	Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	37-42	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	102-107	
29110251-7	2018	After pretreatment with AG490 (50 muM) which led to blocking of the JAK/STAT signal pathway, the reductive expressions of Mcl-1, STAT3 and p-STAT3 caused by fucoxanthin were inhibited.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	24-29	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	122-127	
19968719-10	2010	Inhibition of STAT3 activation by JAK inhibitor AG490 decreased Mcl-1 expression and induced apoptosis in STAT3-active NK-YS cells.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	48-53	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	64-69	
16317687-5	2005	Treatment with anti-IL-6 antisera or the JAK inhibitor AG490 or transfection with dominant negative STAT3 diminished Mcl-1 messenger RNA and protein levels.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	55-60	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	117-122	
12466961-5	2002	Janus kinase inhibitor AG490 inhibits Stat3 activation with a concomitant reduction in steady-state levels of Bcl-X(L), Bcl-2 and Mcl-1 proteins and induces apoptosis in U251 cells as revealed by Poly (ADP-ribose) polymerase cleavage and Annexin-V staining.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	23-28	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	130-135