PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19592641-8 2009 Blocking IL-4 signaling during the decay phase using the JAK inhibitor AG490 or the anti-IL-4R(alpha) Ab M1 abrogated the persistence of phosphorylated STAT6 observed in the V50-IL-4R(alpha)-expressing cells. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 71-76 interleukin 4 Homo sapiens 9-13 22992805-8 2013 The IL-4-induced downregulation of melanogenesis was inhibited by treating NHMs with a JAK2 inhibitor AG490 or STAT6 siRNA. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 102-107 interleukin 4 Homo sapiens 4-8 17264307-6 2007 We also demonstrated that IL-4 induced phosphorylation of Syk, p38, Erk-1/2, JNK, Jak-1, Jak-2, STAT6, and STAT1 and that treatment of cells with the inhibitors piceatannol, SB203580, PD98059, or AG490 reversed the ability of IL-4 to delay neutrophil apoptosis. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 196-201 interleukin 4 Homo sapiens 26-30 16210363-9 2006 The actions of interferon-gamma and IL-4 are mediated through the Janus kinase 2/signal transducer and activator of transcription signaling pathway and could be abolished by treating with AG490, a specific inhibitor of Janus kinase 2. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 188-193 interleukin 4 Homo sapiens 36-40 11709700-6 2001 We show that IL-4 or IL-13-induced IL-13Ralpha2 mRNA expression was inhibited by the ERK inhibitor U0126, the JAK inhibitor AG490 and, to a lesser extent, the p38 MAPK inhibitor SB203580. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 124-129 interleukin 4 Homo sapiens 13-17 10845915-4 2000 AG-490 potently inhibited IL-4-mediated proliferation of both D10 and the IL-4-dependent cell line CT.4S. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 0-6 interleukin 4 Homo sapiens 26-30 10845915-4 2000 AG-490 potently inhibited IL-4-mediated proliferation of both D10 and the IL-4-dependent cell line CT.4S. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 0-6 interleukin 4 Homo sapiens 74-78