PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11117534-11	2000	The JAK2 inhibitor AG490 blocked phosphorylation of STAT5 and PRL-induced, but not PGE1-induced, Cl- transport.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	19-24	signal transducer and activator of transcription 5A	Mus musculus	52-57	
16775227-6	2006	The JAK inhibitor Ag490 reduced both the developmental rate of the embryos and the expression levels of the downstream genes of the JAK-STAT5 signaling pathway.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	18-23	signal transducer and activator of transcription 5A	Mus musculus	136-141	
11046040-3	2000	We recently reported that tyrphostin AG-490 selectively blocked IL-2 activation of Jak3/Stat5 and growth of murine T cell lines.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	26-43	signal transducer and activator of transcription 5A	Mus musculus	88-93	
24688026-10	2014	Numbers of p-STAT3(+) CD4(+) T cells and p-STAT5(+) CD4(+) T cells were reduced and elevated, respectively, after treatment with AG490.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	129-134	signal transducer and activator of transcription 5A	Mus musculus	43-48	
22969062-6	2012	Inhibition of JAK (STAT1/STAT5 kinase) with AG490 markedly reduced the production of IL-6 and TNF-alpha in macrophages.	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	44-49	signal transducer and activator of transcription 5A	Mus musculus	25-30