PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23620191-8 2013 The blockage of STAT3 phosphorylation using a specific inhibitor (AG490) suppressed the irradiation-induced elevation of MMP-2 expression, enzyme activity and invasion of A549 cells. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 66-71 matrix metallopeptidase 2 Homo sapiens 121-126 31912690-5 2019 The effects of AG490 on the expression of STAT3, p-STAT3, MMP2 and Cyclin D1 in Pumc-91 were evaluated using qRT-PCR and Western blot. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 15-20 matrix metallopeptidase 2 Homo sapiens 58-62 31966644-10 2017 Suppression of JAK2/STAT3 pathway by AG490 attenuated the promotive effects of IL-9 on SMMC-7721 cells, and reduced the expression of VEGF, MMP-2 and MMP-9. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 37-42 matrix metallopeptidase 2 Homo sapiens 140-145 32793721-14 2020 IL-17a neutralizing antibody or JAK2 inhibitor AG490 can significantly inhibit the effects of CAFs on the migration, invasion, MMP2/9, TIMP1/2, and JAK2/STAT3 pathways of GC cells. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 47-52 matrix metallopeptidase 2 Homo sapiens 127-133 25628937-5 2015 Compared to control group,there were less tumor cells permeating membrane and less formed tubes after curcumin or AG490 treatment, RT-PCR showed that the expression of MMP-2 and VEGF at mRNA level were decreased (P < 0.01). alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 114-119 matrix metallopeptidase 2 Homo sapiens 168-173