PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26512898-0 2015 Inhibition on Proteasome beta1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells. fangchinoline 86-99 proteasome 20S subunit beta 1 Homo sapiens 14-38 26512898-2 2015 Fangchinoline and its structure analogue, tetrandrine, exhibited direct binding affinity with recombinant human proteasome beta1 subunit and also inhibited its activity in vitro. fangchinoline 0-13 proteasome 20S subunit beta 1 Homo sapiens 112-136 26512898-3 2015 In cultured prostate PC-3 cells and LnCap cells, fangchinoline could dose-dependently inhibit cell proliferation and caspase-like activity of cellular proteasome which was mediated by proteasome beta1 subunit. fangchinoline 49-62 proteasome 20S subunit beta 1 Homo sapiens 184-208 26512898-8 2015 Over-expression of proteasome beta1 subunit by plasmid transfection increased sensitivity of cells to the cytotoxicity of fangchinoline while knockdown of proteasome beta1 subunit ameliorated cytotoxicity of fangchinoline in PC-3 cells. fangchinoline 122-135 proteasome 20S subunit beta 1 Homo sapiens 19-43 26512898-8 2015 Over-expression of proteasome beta1 subunit by plasmid transfection increased sensitivity of cells to the cytotoxicity of fangchinoline while knockdown of proteasome beta1 subunit ameliorated cytotoxicity of fangchinoline in PC-3 cells. fangchinoline 208-221 proteasome 20S subunit beta 1 Homo sapiens 19-43 26512898-8 2015 Over-expression of proteasome beta1 subunit by plasmid transfection increased sensitivity of cells to the cytotoxicity of fangchinoline while knockdown of proteasome beta1 subunit ameliorated cytotoxicity of fangchinoline in PC-3 cells. fangchinoline 208-221 proteasome 20S subunit beta 1 Homo sapiens 155-179