PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21418191-0 2011 Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells. fangchinoline 0-13 tumor protein p53 Homo sapiens 48-51 21418191-6 2011 Nuclear translocation of p53 was involved in induction of autophagy by fangchinoline, followed by selective transactivation of the autophagy-related gene sestrin2 and initiation of the autophagic process. fangchinoline 71-84 tumor protein p53 Homo sapiens 25-28 21418191-8 2011 siRNA for Atg 5 or pharmacological block of p53 abolished fangchinoline-induced autophagy and inhibition of autophagy switched cell death to apoptosis in these cells, suggesting that cell death is irreversible once autophagy is induced by fangchinoline. fangchinoline 58-71 tumor protein p53 Homo sapiens 44-47