PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12460238-0 2002 Myasthenia gravis after allogeneic bone marrow transplantation treated with mycophenolate mofetil monitored by peripheral blood OX40+ CD4+ T cells. Mycophenolic Acid 76-97 CD4 molecule Homo sapiens 134-137 12460238-2 2002 OX40+CD4+ T cells in the peripheral blood prominently increased one month before the onset of MG. CD4/CD8 ratios, usually abnormally inverted in patients with chronic graft-vs.-host disease (cGVHD), showed pseudonormalization during the course of MG. We succeeded in uneventful rapid tapering of prednisolone (PSL) using mycophenolate mofetil (MMF). Mycophenolic Acid 321-342 CD4 molecule Homo sapiens 5-8 12460238-2 2002 OX40+CD4+ T cells in the peripheral blood prominently increased one month before the onset of MG. CD4/CD8 ratios, usually abnormally inverted in patients with chronic graft-vs.-host disease (cGVHD), showed pseudonormalization during the course of MG. We succeeded in uneventful rapid tapering of prednisolone (PSL) using mycophenolate mofetil (MMF). Mycophenolic Acid 321-342 CD4 molecule Homo sapiens 98-101 12460238-2 2002 OX40+CD4+ T cells in the peripheral blood prominently increased one month before the onset of MG. CD4/CD8 ratios, usually abnormally inverted in patients with chronic graft-vs.-host disease (cGVHD), showed pseudonormalization during the course of MG. We succeeded in uneventful rapid tapering of prednisolone (PSL) using mycophenolate mofetil (MMF). Mycophenolic Acid 344-347 CD4 molecule Homo sapiens 5-8 12460238-2 2002 OX40+CD4+ T cells in the peripheral blood prominently increased one month before the onset of MG. CD4/CD8 ratios, usually abnormally inverted in patients with chronic graft-vs.-host disease (cGVHD), showed pseudonormalization during the course of MG. We succeeded in uneventful rapid tapering of prednisolone (PSL) using mycophenolate mofetil (MMF). Mycophenolic Acid 344-347 CD4 molecule Homo sapiens 98-101 11035376-1 2000 Instead of donor T cell depletion, we used CTLA4 and TJU103 (a small organic compound believed to block CD4 binding to MHC II molecule of APC) to block donor T lymphocyte activation in vitro before infusion, and mycophenolate mofetil to control the activity of lymphocytes of the recipient. Mycophenolic Acid 212-233 CD4 molecule Homo sapiens 104-107 11328741-0 2001 CD69 expression on peripheral CD4+ T cells parallels disease activity and is reduced by mycophenolate mofetil therapy in uveitis. Mycophenolic Acid 88-109 CD4 molecule Homo sapiens 30-33 7544050-1 1995 Mycophenolic acid (MPA), an inhibitor of inosine monophosphate dehydrogenase, shows strong anti-HIV activity in vitro in both human peripheral blood CD4+ lymphocytes and macrophages, as well as established human cell lines. Mycophenolic Acid 0-17 CD4 molecule Homo sapiens 149-152 10083559-0 1999 Mycophenolate mofetil impairs transendothelial migration of allogeneic CD4 and CD8 T-cells. Mycophenolic Acid 0-21 CD4 molecule Homo sapiens 71-74 7544050-1 1995 Mycophenolic acid (MPA), an inhibitor of inosine monophosphate dehydrogenase, shows strong anti-HIV activity in vitro in both human peripheral blood CD4+ lymphocytes and macrophages, as well as established human cell lines. Mycophenolic Acid 19-22 CD4 molecule Homo sapiens 149-152 27569951-5 2016 CD4(+) T-cell iATP level in the FK506 group and FK506 + prednisone (Pred) groups was higher than in the FK506 + mycophenolate mofetil (MMF), FK506 + MMF + Pred, and rapamycin (Rapa) groups. Mycophenolic Acid 135-138 CD4 molecule Homo sapiens 0-3 31651849-4 2019 The influence of mycophenolic acid (MPA) derivatives and prednisone on p70S6 kinase phosphorylation in CD4-positive cells was examined in liver transplant patients and healthy controls (HCs). Mycophenolic Acid 17-34 CD4 molecule Homo sapiens 103-106 31651849-4 2019 The influence of mycophenolic acid (MPA) derivatives and prednisone on p70S6 kinase phosphorylation in CD4-positive cells was examined in liver transplant patients and healthy controls (HCs). Mycophenolic Acid 36-39 CD4 molecule Homo sapiens 103-106 32779952-0 2022 Comparison of CD4 Counts with Mycophenolate Mofetil versus Methotrexate from the First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial. Mycophenolic Acid 30-51 CD4 molecule Homo sapiens 14-17 32779952-1 2022 PURPOSE: Sub-analysis of the FAST Trial comparing change in CD4 ( CD4) from baseline through 12 months in uveitis patients treated with mycophenolate mofetil (MMF) and methotrexate (MTX). Mycophenolic Acid 136-157 CD4 molecule Homo sapiens 60-63 32779952-1 2022 PURPOSE: Sub-analysis of the FAST Trial comparing change in CD4 ( CD4) from baseline through 12 months in uveitis patients treated with mycophenolate mofetil (MMF) and methotrexate (MTX). Mycophenolic Acid 136-157 CD4 molecule Homo sapiens 66-69 27569951-5 2016 CD4(+) T-cell iATP level in the FK506 group and FK506 + prednisone (Pred) groups was higher than in the FK506 + mycophenolate mofetil (MMF), FK506 + MMF + Pred, and rapamycin (Rapa) groups. Mycophenolic Acid 149-152 CD4 molecule Homo sapiens 0-3 23146536-4 2012 We investigated here in, the effect of mycophenolate mofetil (MMF) and corticosteroids, usually used in combination with a calcineurin inhibitor on human CD4(+)CD25(+) Treg cells. Mycophenolic Acid 39-60 CD4 molecule Homo sapiens 154-157 25549254-0 2015 Relationship between the Peripheral Lymphocyte Response to Mycophenolic Acid in vitro and the Level of ATP in Peripheral CD4+ Lymphocytes before and after Renal Transplantation. Mycophenolic Acid 59-76 CD4 molecule Homo sapiens 121-124 24222014-0 2014 Mycophenolic acid-treated dendritic cells generate regulatory CD4+ T cells that suppress CD8+ T cells" allocytotoxicity. Mycophenolic Acid 0-17 CD4 molecule Homo sapiens 62-65 24222014-4 2014 CD8(+) T cells are major agents in the rejection of allografts; the aim of this study is to investigate the effects exerted on CD8(+) T cells by human CD4(+) iTreg induced by mycophenolic acid-treated dendritic cells. Mycophenolic Acid 175-192 CD4 molecule Homo sapiens 151-154 25661834-0 2015 Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4+T cells. Mycophenolic Acid 0-17 CD4 molecule Homo sapiens 66-69 23146536-4 2012 We investigated here in, the effect of mycophenolate mofetil (MMF) and corticosteroids, usually used in combination with a calcineurin inhibitor on human CD4(+)CD25(+) Treg cells. Mycophenolic Acid 62-65 CD4 molecule Homo sapiens 154-157 21342445-0 2011 Mycophenolic acid-mediated suppression of human CD4+ T cells: more than mere guanine nucleotide deprivation. Mycophenolic Acid 0-17 CD4 molecule Homo sapiens 48-51 21976399-0 2012 Progressive multifocal leukoencephalopathy associated with mycophenolate mofetil treatment in a woman with lupus and CD4+ T-lymphocyte deficiency. Mycophenolic Acid 59-80 CD4 molecule Homo sapiens 117-120 21342445-3 2011 Here, we present novel insights into the mechanisms underlying mycophenolic acid-mediated suppression of human CD4+ T cells. Mycophenolic Acid 63-80 CD4 molecule Homo sapiens 111-114 19352129-0 2009 Conversion from calcineurin inhibitor to mycophenolate mofetil-based immunosuppression changes the frequency and phenotype of CD4+FOXP3+ regulatory T cells. Mycophenolic Acid 41-62 CD4 molecule Homo sapiens 126-129 19398001-1 2009 We evaluated whether the regulatory function of CD4(+)CD25(high+)FoxP3(+) T-cells from patients on tacrolimus and mycophenolate mofetil (MMF) is affected by preceding steroid and anti-CD25 mAb induction therapy and whether this function is associated with rejection after kidney transplantation. Mycophenolic Acid 114-135 CD4 molecule Homo sapiens 48-51 19398001-1 2009 We evaluated whether the regulatory function of CD4(+)CD25(high+)FoxP3(+) T-cells from patients on tacrolimus and mycophenolate mofetil (MMF) is affected by preceding steroid and anti-CD25 mAb induction therapy and whether this function is associated with rejection after kidney transplantation. Mycophenolic Acid 137-140 CD4 molecule Homo sapiens 48-51 18611986-0 2008 Induction of human CD4+ regulatory T cells by mycophenolic acid-treated dendritic cells. Mycophenolic Acid 46-63 CD4 molecule Homo sapiens 19-22 17038874-0 2006 Determination of inosine monophosphate dehydrogenase activity in human CD4+ cells isolated from whole blood during mycophenolic acid therapy. Mycophenolic Acid 115-132 CD4 molecule Homo sapiens 71-74