PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8086032-7 1994 The excessive growth could be blocked by PDMP, which competes with UDP-glc for binding to glucosylceramide synthase. Uridine Diphosphate Glucose 67-74 UDP-glucose ceramide glucosyltransferase Homo sapiens 90-115 2144831-2 1990 The removal of phospholipids completely abolished the activity of the enzyme UDP-glucose:ceramide glucosyltransferase from Golgi membranes. Uridine Diphosphate Glucose 77-88 UDP-glucose ceramide glucosyltransferase Homo sapiens 89-117 29627573-6 2018 PtdIns(4)P inhibited UGCG activity, but not SMS activity, in a concentration-dependent manner, and UGCG activity was restored by the addition of UDP-glucose in the reaction mixture. Uridine Diphosphate Glucose 145-156 UDP-glucose ceramide glucosyltransferase Homo sapiens 99-103 6811701-6 1982 Activity of the control enzyme UDP-glucose:ceramide glucosyltransferase was always normal in both the spinal cord and kidney. Uridine Diphosphate Glucose 31-42 UDP-glucose ceramide glucosyltransferase Homo sapiens 43-71 29627573-7 2018 These results indicate that PtdIns(4)P inhibits UGCG activity by competing with UDP-glucose. Uridine Diphosphate Glucose 80-91 UDP-glucose ceramide glucosyltransferase Homo sapiens 48-52 23073611-6 2013 GlcCer, generated by glucosylceramide synthase (GCS) that transfers the glucose from UDP-glucose to ceramide, is an important glycosphingolipid metabolic intermediate. Uridine Diphosphate Glucose 85-96 UDP-glucose ceramide glucosyltransferase Homo sapiens 21-46 28739255-5 2017 Moreover, the modes of inhibition of ceramide glucosyltransferase were uncompetitive with respect to both C6-NBD-cermide and UDP-glucose. Uridine Diphosphate Glucose 125-136 UDP-glucose ceramide glucosyltransferase Homo sapiens 37-65 23181473-4 2013 GCS, a key enzyme of this pathway, neutralizes pro-apoptotic ceramide by transfer of a uridine diphosphate (UDP)-glucose. Uridine Diphosphate Glucose 108-120 UDP-glucose ceramide glucosyltransferase Homo sapiens 0-3 23073611-6 2013 GlcCer, generated by glucosylceramide synthase (GCS) that transfers the glucose from UDP-glucose to ceramide, is an important glycosphingolipid metabolic intermediate. Uridine Diphosphate Glucose 85-96 UDP-glucose ceramide glucosyltransferase Homo sapiens 48-51 21538359-1 2011 BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer. Uridine Diphosphate Glucose 128-139 UDP-glucose ceramide glucosyltransferase Homo sapiens 68-93 21538359-1 2011 BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer. Uridine Diphosphate Glucose 128-139 UDP-glucose ceramide glucosyltransferase Homo sapiens 95-98 22563139-2 2010 This glucosylceramide analogue acts as an inhibitor of glucosylceramide synthase, a Golgi complex enzyme that catalyzes the formation of glucosylceramide from ceramide and UDP-glucose and is the first step in the formation of glucocerebroside-based glycosphingolipids. Uridine Diphosphate Glucose 172-183 UDP-glucose ceramide glucosyltransferase Homo sapiens 55-80 10869565-0 2000 Regulation of UDP-glucose:ceramide glucosyltransferase-1 by ceramide. Uridine Diphosphate Glucose 14-25 UDP-glucose ceramide glucosyltransferase Homo sapiens 35-56 10869565-1 2000 We report that the expression of mRNA and the activity of UDP-glucose:ceramide (Cer) glucosyltransferase-1 (GlcT-1) of human hepatoma Huh7 and mouse melanoma B16 cells increases after treatment with bacterial sphingomyelinase or upon addition of short-chain Cer. Uridine Diphosphate Glucose 58-69 UDP-glucose ceramide glucosyltransferase Homo sapiens 85-106 10869565-1 2000 We report that the expression of mRNA and the activity of UDP-glucose:ceramide (Cer) glucosyltransferase-1 (GlcT-1) of human hepatoma Huh7 and mouse melanoma B16 cells increases after treatment with bacterial sphingomyelinase or upon addition of short-chain Cer. Uridine Diphosphate Glucose 58-69 UDP-glucose ceramide glucosyltransferase Homo sapiens 108-114 9143336-4 1997 Although the formation of glucosylceramide was detected and characterized, several lines of evidence contradicted the assumption that UDP-glucose is the immediate glucose donor for glucosylceramide formation in plants: PDMP (DL-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol), an inhibitor of ceramide glucosyltransferase in animal tissues, did not inhibit glucosylceramide formation in bean microsomes. Uridine Diphosphate Glucose 134-145 UDP-glucose ceramide glucosyltransferase Homo sapiens 301-329