PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32077313-4	2021	PolyP-induced NF-kappaB activation and the productions of TNF-alpha and IL-6 were inhibited by aloin in HUVECs.	alloin	95-100	interleukin 6	Homo sapiens	72-76	
33839199-19	2021	Finally, we discovered that treat with aloin A markedly decreased IL-6 levels and increased MUC2 expression in LPS-stimulated LS174T cell.	alloin	39-46	interleukin 6	Homo sapiens	66-70	
33502605-8	2021	Additionally, the elevated pro-inflammatory cytokine levels were counteracted after aloin treatment in cells under SI/R conditions, including TNF-alpha, IL-6, and IL-1beta.	alloin	84-89	interleukin 6	Homo sapiens	153-157	
33096361-4	2020	In in-vitro experiments, the protective effect of aloin on the anabolism and catabolism of the extracellular matrix (ECM) induced by IL-1 beta in chondrocytes by inhibiting the expression of pro-inflammatory factors, including TNF-alpha (p = 0.016), IL-6 (p = 0.006), iNOS (p = 0.001) and COX-2 (p = 0.006).	alloin	50-55	interleukin 6	Homo sapiens	250-254	
29495390-4	2018	In this report, we found that aloin suppresses lipopolysaccharide-induced pro-inflammatory cytokine secretion and nitric oxide production, and downregulates the expression of tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2).	alloin	30-35	interleukin 6	Homo sapiens	216-229	
29495390-4	2018	In this report, we found that aloin suppresses lipopolysaccharide-induced pro-inflammatory cytokine secretion and nitric oxide production, and downregulates the expression of tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2).	alloin	30-35	interleukin 6	Homo sapiens	231-235