PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25609833-4	2015	Dexra is a catalytic topoisomerase 2 inhibitor that protects the mouse ovary from acute doxorubicin (DXR) chemotherapy toxicity in vitro by preventing DXR-induced DNA damage and subsequent gammaH2AX activation.	Dexrazoxane	0-5	H2A.X variant histone	Mus musculus	189-198	
25609833-8	2015	DXR treatment for 24 h increased gammaH2AX phosphorylation, specifically increasing the number of foci-positive granulosa cells in antral follicles, while Dexra pretreatment inhibited DXR-induced gammaH2AX phosphorylation foci formation.	Dexrazoxane	155-160	H2A.X variant histone	Mus musculus	196-205	
17875725-5	2007	In the present study, we showed that dexrazoxane specifically abolished the DNA damage signal gamma-H2AX induced by doxorubicin, but not camptothecin or hydrogen peroxide, in H9C2 cardiomyocytes.	Dexrazoxane	37-48	H2A.X variant histone	Mus musculus	94-104