PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32023632-0	2020	Destabilization of FoxM1 and Inhibition of Topoisomerase I Contribute to Cytotoxicity of Prenylated Xanthones Isolated from Metaxya rostrata.	Xanthones	100-109	forkhead box M1	Homo sapiens	19-24	
32023632-2	2020	This study explores the mechanisms underlying the FoxM1 downregulation induced by both xanthones.	Xanthones	87-96	forkhead box M1	Homo sapiens	50-55	
32023632-3	2020	Analysis of cell viability and cell-death induction in SW480, HCT116, Caco-2, DLD1 and HT29 exposed to xanthones found cell-loss and activation of caspase in all cell lines except HT29 that do not have high FoxM1 protein levels.	Xanthones	103-112	forkhead box M1	Homo sapiens	207-212	
32023632-4	2020	To determine the cellular mechanism of xanthone-induced FoxM1 loss, protein stability was analyzed by cycloheximide-chase experiments and showed reduction of FoxM1 stability by XB but not OH-XB.	Xanthones	39-47	forkhead box M1	Homo sapiens	56-61	
32023632-4	2020	To determine the cellular mechanism of xanthone-induced FoxM1 loss, protein stability was analyzed by cycloheximide-chase experiments and showed reduction of FoxM1 stability by XB but not OH-XB.	Xanthones	39-47	forkhead box M1	Homo sapiens	158-163	
32023632-8	2020	This may reduce FoxM1 gene expression, which may in turn compromise DNA repair and enhance xanthone-induced cell death.	Xanthones	91-99	forkhead box M1	Homo sapiens	16-21