PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24652148-2 2014 Most often binding to serine, tyrosine, or threonine residues is described as being of relevance for toxicological effects (e.g., acetylcholinesterase and neuropathy target esterase) or as biomarkers for post-exposure analysis (verification, e.g., albumin and butyrylcholinesterase). Serine 22-28 patatin like phospholipase domain containing 6 Homo sapiens 155-181 27317427-6 2016 Knockdown of PNPLA9, PNPLA6 or PNPLA4 significantly (30-50%) reduced the turnover of phosphatidylcholine, -ethanolamine and -serine. Serine 125-131 patatin like phospholipase domain containing 6 Homo sapiens 21-27 10816586-3 2000 NEST comprises residues 727-1216 of human NTE, and site-directed mutagenesis revealed that serine 966 and two aspartate residues, Asp(1086) and Asp(960), are critical for catalysis. Serine 91-97 patatin like phospholipase domain containing 6 Homo sapiens 42-45 16137924-1 2005 Certain organophosphates react with the active site serine residue of neuropathy target esterase (NTE) and cause axonal degeneration and paralysis. Serine 52-58 patatin like phospholipase domain containing 6 Homo sapiens 98-101 10759065-8 2000 Neuropathic OPs react covalently with NTE in a rapid two-step process which not only inhibits catalytic activity but also leaves a negatively-charged OP group attached to the active site serine. Serine 187-193 patatin like phospholipase domain containing 6 Homo sapiens 38-41 9576844-1 1998 The N-terminal amino acid sequences of proteolytic fragments of neuropathy target esterase (NTE), covalently labelled on its active-site serine by a biotinylated organophosphorus ester, were determined and used to deduce the location of this serine residue and to initiate cloning of its cDNA. Serine 137-143 patatin like phospholipase domain containing 6 Homo sapiens 92-95 9576844-1 1998 The N-terminal amino acid sequences of proteolytic fragments of neuropathy target esterase (NTE), covalently labelled on its active-site serine by a biotinylated organophosphorus ester, were determined and used to deduce the location of this serine residue and to initiate cloning of its cDNA. Serine 242-248 patatin like phospholipase domain containing 6 Homo sapiens 92-95 9576844-2 1998 A putative NTE clone, isolated from a human foetal brain cDNA library, encoded a 1327 residue polypeptide with no homology to any known serine esterases or proteases. Serine 136-142 patatin like phospholipase domain containing 6 Homo sapiens 11-14 9576844-3 1998 The active-site serine of NTE (Ser-966) lay in the centre of a predicted hydrophobic helix within a 200-amino-acid C-terminal domain with marked similarity to conceptual proteins in bacteria, yeast and nematodes; these proteins may comprise a novel family of potential serine hydrolases. Serine 16-22 patatin like phospholipase domain containing 6 Homo sapiens 26-29 9576844-3 1998 The active-site serine of NTE (Ser-966) lay in the centre of a predicted hydrophobic helix within a 200-amino-acid C-terminal domain with marked similarity to conceptual proteins in bacteria, yeast and nematodes; these proteins may comprise a novel family of potential serine hydrolases. Serine 31-34 patatin like phospholipase domain containing 6 Homo sapiens 26-29 9576844-3 1998 The active-site serine of NTE (Ser-966) lay in the centre of a predicted hydrophobic helix within a 200-amino-acid C-terminal domain with marked similarity to conceptual proteins in bacteria, yeast and nematodes; these proteins may comprise a novel family of potential serine hydrolases. Serine 269-275 patatin like phospholipase domain containing 6 Homo sapiens 26-29