PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33863812-4 2021 The screen revealed that sgRNAs targeting the serine/threonine kinase CHK2 were enriched following olaparib treatment. Serine 46-52 checkpoint kinase 2 Mus musculus 70-74 31676238-2 2020 Wild-type p53-induced phosphatase 1 (Wip1) is a p53-inducible serine/threonine phosphatase that terminates DNA-damage responses via dephosphorylation of DNA-damage response proteins, namely ataxia-telangiectasia mutated (ATM) kinase, checkpoint kinase 2, and p53, thus enhancing cell proliferation. Serine 62-68 checkpoint kinase 2 Mus musculus 234-253 15485917-2 2004 After DNA damage, BRCA1 is phosphorylated by CHK2 at serine 988, followed by a change in its intracellular location. Serine 53-59 checkpoint kinase 2 Mus musculus 45-49 14752107-5 2004 Using wortmannin, serine 15 mutants of p53, DNA-PK null cells and Chk2 null cells, we demonstrate that DNA-PK and Chk2 act independently and sequentially on p53. Serine 18-24 checkpoint kinase 2 Mus musculus 114-118 10710310-7 2000 Chk2 directly phosphorylated p53 on serine 20, which is known to interfere with Mdm2 binding. Serine 36-42 checkpoint kinase 2 Mus musculus 0-4