PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9335504-4	1997	Phosphorylation occurs at specific serines within the region linking the inhibitory and effector domains of Smad1, and is catalysed by the Erk family of mitogen-activated protein kinases.	Serine	35-42	SMAD family member 1	Homo sapiens	108-113	
9335504-5	1997	In contrast to the BMP-stimulated phosphorylation of Smad1, which affects carboxy-terminal serines and induces nuclear accumulation of Smad1, Erk-mediated phosphorylation specifically inhibits the nuclear accumulation of Smad1.	Serine	91-98	SMAD family member 1	Homo sapiens	53-58	
25937027-10	2015	HB-EGF activated the ERK and p38 MAP kinases and stimulated phosphorylation of Smad1 at an inhibitory serine site which was associated with inhibition of OP-1 mediated proteoglycan synthesis and reduced aggrecan (ACAN) but not COL2A1 expression.	Serine	102-108	SMAD family member 1	Homo sapiens	79-84	
9136927-5	1997	Phosphorylation of Smad1 in vivo involves serines in the carboxy-terminal motif SSXS.	Serine	42-49	SMAD family member 1	Homo sapiens	19-24	
9136927-7	1997	Mutation of these carboxy-terminal serines prevents several Smad1 activation events, namely, Smad1 association with the related protein DPC4, accumulation in the nucleus, and gain of transcriptional activity.	Serine	35-42	SMAD family member 1	Homo sapiens	60-65	
9136927-7	1997	Mutation of these carboxy-terminal serines prevents several Smad1 activation events, namely, Smad1 association with the related protein DPC4, accumulation in the nucleus, and gain of transcriptional activity.	Serine	35-42	SMAD family member 1	Homo sapiens	93-98	
8663601-0	1996	Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1.	Serine	0-6	SMAD family member 1	Homo sapiens	115-120	
25469313-11	2014	The role of preconditioning with BMP2 in osteogenesis was validated by findings of increased gene expression of SMAD1 and an increase in dual phosphorylation of ser 463 and ser 465 in the SMAD 1/5/8 pathway.	Serine	173-176	SMAD family member 1	Homo sapiens	188-196	
25469313-11	2014	The role of preconditioning with BMP2 in osteogenesis was validated by findings of increased gene expression of SMAD1 and an increase in dual phosphorylation of ser 463 and ser 465 in the SMAD 1/5/8 pathway.	Serine	161-164	SMAD family member 1	Homo sapiens	188-196	
18436795-7	2008	The mechanism involves ERK1/2-dependent phosphorylation of the Smad1 linker region (serine 206), which limits C-terminal serine 463/465 phosphorylation and inhibits Smad nuclear accumulation.	Serine	84-90	SMAD family member 1	Homo sapiens	63-68	
24664641-10	2014	Oxidative stress also increased p38 phosphorylation, which resulted in phosphorylation of Smad1 at the Ser(206) inhibitory site and reduced nuclear accumulation of Smad1.	Serine	103-106	SMAD family member 1	Homo sapiens	90-95	
22021003-5	2012	Deletion analyses of Zranb2 indicated that the serine/arginine-rich (SR) domain and the glutamine-rich domain were required for the inhibition of BMP activity and the interaction with Smad1, respectively.	Serine	47-53	SMAD family member 1	Homo sapiens	184-189	
19594322-1	2010	Phosphorylation of Smad1/5/8 at carboxyl-terminal serine residues by type I receptors activates downstream bone morphogenetic protein (BMP) signaling.	Serine	50-56	SMAD family member 1	Homo sapiens	19-26	
18436795-7	2008	The mechanism involves ERK1/2-dependent phosphorylation of the Smad1 linker region (serine 206), which limits C-terminal serine 463/465 phosphorylation and inhibits Smad nuclear accumulation.	Serine	84-90	SMAD family member 1	Homo sapiens	63-67	
18436795-7	2008	The mechanism involves ERK1/2-dependent phosphorylation of the Smad1 linker region (serine 206), which limits C-terminal serine 463/465 phosphorylation and inhibits Smad nuclear accumulation.	Serine	121-127	SMAD family member 1	Homo sapiens	63-68	
18436795-7	2008	The mechanism involves ERK1/2-dependent phosphorylation of the Smad1 linker region (serine 206), which limits C-terminal serine 463/465 phosphorylation and inhibits Smad nuclear accumulation.	Serine	121-127	SMAD family member 1	Homo sapiens	63-67	
17363596-3	2007	Expression of dominant-negative Smad1, in which serines at the COOH-terminal SSVS motif are converted to alanines, suppressed MIS-induced Smad1 phosphorylation and impaired MIS-stimulated Gro-beta promoter-driven reporter expression and Gro-beta mRNA.	Serine	48-55	SMAD family member 1	Homo sapiens	32-37	
11509558-3	2001	BMP addition triggers Smad1 serine phosphorylation, binding of Smad4, and its accumulation in the nucleus.	Serine	28-34	SMAD family member 1	Homo sapiens	22-27