PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31496721-7 2019 Results: Our results indicated that kurarinone significantly decreased H1688 cell viability and induced the accumulation of sub-G1 fractions by activating caspase-3, -9, and PARP cleavage accompanied by the elevated release of cytochrome c and mitochondrial dysfunction in H1688 cells. kurarinone 36-46 caspase 3 Homo sapiens 155-168 29628889-6 2018 Mechanistically, kurarinone significantly decreased the ratio of Bcl-2/Bax, thereby causing the activation of caspase 9 and caspase 3, and reduced the expression of Grp78, which led to relieve the inhibition of caspase-12 and caspase-7, as well as suppressing the activity of AKT. kurarinone 17-27 caspase 3 Homo sapiens 124-133