PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30421460-0	2019	Calycosin attenuates MPTP-induced Parkinson"s disease by suppressing the activation of TLR/NF-kappaB and MAPK pathways.	7,3'-dihydroxy-4'-methoxyisoflavone	0-9	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	91-100	
34908806-15	2021	CONCLUSION: Cal protects mice against L-arg-induced SAP and associated ALI by attenuating local and systemic neutrophil infiltration and inflammatory response via inhibition of HGMB1 and the NF-kappaB signaling pathway.	7,3'-dihydroxy-4'-methoxyisoflavone	12-15	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	191-200	
30830898-0	2019	Calycosin Ameliorates Diabetes-Induced Renal Inflammation via the NF-kappaB Pathway In Vitro and In Vivo.	7,3'-dihydroxy-4'-methoxyisoflavone	0-9	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	66-75	
30830898-9	2019	Mechanistically, we identified calycosin inhibited diabetes-induced inflammation in kidneys by suppressing the phosphorylation of IKBa and NF-kappaB p65 in vitro and in vivo.	7,3'-dihydroxy-4'-methoxyisoflavone	31-40	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	139-148	
30830898-10	2019	CONCLUSIONS Calycosin significantly ameliorated diabetes-induced renal inflammation in diabetic renal injury by inhibition of the NF-kappaB-dependent signaling pathway in vivo and in vitro.	7,3'-dihydroxy-4'-methoxyisoflavone	12-21	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	130-139	
30421460-13	2019	The TLR/NF-kappaB and MAPK pathways in MPTP-induced PD mice were inhibited by calycosin treatment, which was coincident with experiments in LPS-induced BV2 cells.	7,3'-dihydroxy-4'-methoxyisoflavone	78-87	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	8-17	
30421460-14	2019	Above all, calycosin mitigates PD symptoms through TLR/NF-kappaB and MAPK pathways in mice and cell lines.	7,3'-dihydroxy-4'-methoxyisoflavone	11-20	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	55-64	
29890468-10	2018	These results suggested that calycosin protects against AP by exerting anti-inflammatory and anti-oxidative stress effects via the p38 MAPK and NF-kappaB signal pathways.	7,3'-dihydroxy-4'-methoxyisoflavone	29-38	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	144-153	
29890468-0	2018	Calycosin alleviates cerulein-induced acute pancreatitis by inhibiting the inflammatory response and oxidative stress via the p38 MAPK and NF-kappaB signal pathways in mice.	7,3'-dihydroxy-4'-methoxyisoflavone	0-9	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	139-148	
29890468-9	2018	Additionally, calycosin significantly reduced cerulein-induced pancreatic edema, inhibited MPO activity and increased superoxide dismutase (SOD) activity, and inhibited the expression of NF-kappaB/p65 and phosphorylation of the inhibitor of NF-kappaB (IkappaBalpha) and p38 MAPK.	7,3'-dihydroxy-4'-methoxyisoflavone	14-23	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	187-196	
29890468-9	2018	Additionally, calycosin significantly reduced cerulein-induced pancreatic edema, inhibited MPO activity and increased superoxide dismutase (SOD) activity, and inhibited the expression of NF-kappaB/p65 and phosphorylation of the inhibitor of NF-kappaB (IkappaBalpha) and p38 MAPK.	7,3'-dihydroxy-4'-methoxyisoflavone	14-23	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	241-250