PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18751388-9	2008	RESULTS: Risedronate inhibited both prenylation of Rap1A and Ras and phosphorylation of Erk 1 and 2 at a dose of 50 microM for 48 h. Treatment with risedronate induced significant time- and dose-dependent cytotoxicity in the LM8 cell line.	Risedronic Acid	9-20	mitogen-activated protein kinase 3	Homo sapiens	88-99	
18751388-9	2008	RESULTS: Risedronate inhibited both prenylation of Rap1A and Ras and phosphorylation of Erk 1 and 2 at a dose of 50 microM for 48 h. Treatment with risedronate induced significant time- and dose-dependent cytotoxicity in the LM8 cell line.	Risedronic Acid	148-159	mitogen-activated protein kinase 3	Homo sapiens	88-99	
15869745-4	2005	Accordingly, risedronate suppressed the phosphorylation of ERK 1/2, a downstream survival signaling kinase of Ras, affected the intracellular distribution of Bcl-xL, and induced the mitochondrial membrane depolarization, cytochrome c release, activated caspase cascade and DNA fragmentation.	Risedronic Acid	13-24	mitogen-activated protein kinase 3	Homo sapiens	59-66