PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32433892-3	2020	Previously, we demonstrated, using drug metabolism enzymes and transporters (DMET) analysis, that the carbohydrate sulfotransferase 3 (CHST3) and CHST13 alleles are significantly more frequent in patients with elevated amino-transferases during therapy with bosentan than they are in patients without liver toxicity.	Bosentan	258-266	carbohydrate sulfotransferase 3	Homo sapiens	102-133	
32433892-3	2020	Previously, we demonstrated, using drug metabolism enzymes and transporters (DMET) analysis, that the carbohydrate sulfotransferase 3 (CHST3) and CHST13 alleles are significantly more frequent in patients with elevated amino-transferases during therapy with bosentan than they are in patients without liver toxicity.	Bosentan	258-266	carbohydrate sulfotransferase 3	Homo sapiens	135-140	
30118797-0	2018	CHST3 and CHST13 polymorphisms as predictors of bosentan-induced liver toxicity in Japanese patients with pulmonary arterial hypertension.	Bosentan	48-56	carbohydrate sulfotransferase 3	Homo sapiens	0-5	
30118797-7	2018	We extracted 16 SNPs (P <  0.05) using the Jonckheere-Terpstra trend test and multiplex logistic analysis; we identified two SNPs in two genes, CHST3 and CHST13, which are responsible for proteoglycan sulfation and were significantly associated with bosentan-induced liver injury.	Bosentan	253-261	carbohydrate sulfotransferase 3	Homo sapiens	147-152