PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30664664-8	2019	Furthermore, ATM loss severely impairs phosphorylation of 53BP1 following co-treatment with CB-5083 and ACY-1215 in response to gamma irradiation.	ricolinostat	104-112	ataxia telangiectasia mutated	Mus musculus	13-16	
34180140-10	2021	These results indicated that ACY1215 exhibited hepatoprotective properties, which was associated with the inhibition of NLRP3 inflammasome, and this effect of ACY1215 was connected with upregulation of the ATM/F-actin mediated signalling pathways.	ricolinostat	29-36	ataxia telangiectasia mutated	Mus musculus	206-209	
34958116-6	2022	Furthermore, ACY-1215 displayed a synergistic effect with specific inhibitors of ATM, an activator of Akt, in inducing cancer cell apoptosis and inhibiting their motility.	ricolinostat	13-21	ataxia telangiectasia mutated	Mus musculus	81-84	
34958116-8	2022	Collectively, our results demonstrated that ACY-1215 is a novel chemotherapeutic agent that could restore mutant p53 function in cancer cells with strong antitumor activity, either alone or in combination with inhibitors of the ATM protein kinase.	ricolinostat	44-52	ataxia telangiectasia mutated	Mus musculus	228-231	
34180140-0	2021	HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F-actin signalling pathway.	ricolinostat	16-23	ataxia telangiectasia mutated	Mus musculus	111-114	
34180140-4	2021	Furthermore, ACY1215 pretreatment increased the level of ATM, gamma-H2AX, Chk2, p53, p21, F-actin and vinculin in ALF.	ricolinostat	13-20	ataxia telangiectasia mutated	Mus musculus	57-60	
34180140-6	2021	The ATM inhibitor KU55933 could decrease the level of ATM, gamma-H2AX, Chk2, p53, p21, F-actin and vinculin in ALF with ACY1215 pretreatment.	ricolinostat	120-127	ataxia telangiectasia mutated	Mus musculus	4-7	
34180140-6	2021	The ATM inhibitor KU55933 could decrease the level of ATM, gamma-H2AX, Chk2, p53, p21, F-actin and vinculin in ALF with ACY1215 pretreatment.	ricolinostat	120-127	ataxia telangiectasia mutated	Mus musculus	54-57	
34180140-10	2021	These results indicated that ACY1215 exhibited hepatoprotective properties, which was associated with the inhibition of NLRP3 inflammasome, and this effect of ACY1215 was connected with upregulation of the ATM/F-actin mediated signalling pathways.	ricolinostat	159-166	ataxia telangiectasia mutated	Mus musculus	206-209