PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30089730-9 2018 Finally, we performed proof-of-principle experiments using a currently approved proteasome inhibitor, ixazomib, to target FOXM1 and demonstrated a therapeutic response in AML patient samples and animal models of AML that correlates with the suppression of FOXM1 and its transcriptional targets. ixazomib 102-110 forkhead box M1 Homo sapiens 122-127 30089730-9 2018 Finally, we performed proof-of-principle experiments using a currently approved proteasome inhibitor, ixazomib, to target FOXM1 and demonstrated a therapeutic response in AML patient samples and animal models of AML that correlates with the suppression of FOXM1 and its transcriptional targets. ixazomib 102-110 forkhead box M1 Homo sapiens 256-261