PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27783987-9 2016 However, the combination of ixazomib with IFN-alpha significantly enhanced ixazomib"s ability to induce apoptotic cell death in BRAF V600E mutant and BRAF wild-type human melanoma tumor cells. ixazomib 75-83 interferon alpha 1 Homo sapiens 42-51 27783987-12 2016 In an in vivo xenograft model of human melanoma, combination treatment with IFN-alpha-2b and ixazomib demonstrated a significant reduction in tumor volume when compared to vehicle (p = 0.005) and single therapy ixazomib (p = 0.017) and IFN-alpha-2b (p = 0.036). ixazomib 93-101 interferon alpha 1 Homo sapiens 236-245 27783987-12 2016 In an in vivo xenograft model of human melanoma, combination treatment with IFN-alpha-2b and ixazomib demonstrated a significant reduction in tumor volume when compared to vehicle (p = 0.005) and single therapy ixazomib (p = 0.017) and IFN-alpha-2b (p = 0.036). ixazomib 211-219 interferon alpha 1 Homo sapiens 76-85