PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27325500-3 2016 When investigating the proteasome inhibitors bortezomib, carfilzomib, and ixazomib, we observed increased luminescence for bortezomib and ixazomib, but not for carfilzomib, in a pregnane-X-receptor (PXR) reporter gene assay, which was inconsistent with the mRNA expression levels of the main PXR target gene CYP3A4. ixazomib 74-82 nuclear receptor subfamily 1 group I member 2 Homo sapiens 178-197 27325500-3 2016 When investigating the proteasome inhibitors bortezomib, carfilzomib, and ixazomib, we observed increased luminescence for bortezomib and ixazomib, but not for carfilzomib, in a pregnane-X-receptor (PXR) reporter gene assay, which was inconsistent with the mRNA expression levels of the main PXR target gene CYP3A4. ixazomib 74-82 nuclear receptor subfamily 1 group I member 2 Homo sapiens 199-202 27325500-3 2016 When investigating the proteasome inhibitors bortezomib, carfilzomib, and ixazomib, we observed increased luminescence for bortezomib and ixazomib, but not for carfilzomib, in a pregnane-X-receptor (PXR) reporter gene assay, which was inconsistent with the mRNA expression levels of the main PXR target gene CYP3A4. ixazomib 74-82 nuclear receptor subfamily 1 group I member 2 Homo sapiens 292-295 27325500-3 2016 When investigating the proteasome inhibitors bortezomib, carfilzomib, and ixazomib, we observed increased luminescence for bortezomib and ixazomib, but not for carfilzomib, in a pregnane-X-receptor (PXR) reporter gene assay, which was inconsistent with the mRNA expression levels of the main PXR target gene CYP3A4. ixazomib 138-146 nuclear receptor subfamily 1 group I member 2 Homo sapiens 178-197 27325500-3 2016 When investigating the proteasome inhibitors bortezomib, carfilzomib, and ixazomib, we observed increased luminescence for bortezomib and ixazomib, but not for carfilzomib, in a pregnane-X-receptor (PXR) reporter gene assay, which was inconsistent with the mRNA expression levels of the main PXR target gene CYP3A4. ixazomib 138-146 nuclear receptor subfamily 1 group I member 2 Homo sapiens 199-202 27325500-3 2016 When investigating the proteasome inhibitors bortezomib, carfilzomib, and ixazomib, we observed increased luminescence for bortezomib and ixazomib, but not for carfilzomib, in a pregnane-X-receptor (PXR) reporter gene assay, which was inconsistent with the mRNA expression levels of the main PXR target gene CYP3A4. ixazomib 138-146 nuclear receptor subfamily 1 group I member 2 Homo sapiens 292-295