PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8706658-9	1996	The 5-lipoxygenase-activating-protein inhibitor, MK-886, was active against both human and mouse recombinant leukotriene C4 synthase with IC50 values of 3.1 microM and 2.7 microM respectively.	MK-886	49-55	leukotriene C4 synthase	Mus musculus	109-132	
12432940-3	2002	The enzyme activity of LTC4S is augmented by Mg2+ and inhibited by Co2+ and the function of 5-lipoxygenase (LO) activating protein (FLAP) inhibitor MK-886.	MK-886	148-154	leukotriene C4 synthase	Mus musculus	23-28	
11748223-4	2002	The biosynthesis of FOG(7) in the macrophage was inhibited by MK-886, a known inhibitor of LTC(4) synthase, suggesting that this nuclear membrane-bound enzyme might be responsible for GSH conjugation to 5-oxoETE in the intact cell.	MK-886	62-68	leukotriene C4 synthase	Mus musculus	91-106