PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30819230-13 2019 Finally, TRPM7 silencing attenuated the PI3K/AKT activation, which was enhanced by BAPTA-AM, MK886 or LY2904002 treatment in ovarian cancer cells. MK-886 93-98 transient receptor potential cation channel subfamily M member 7 Homo sapiens 9-14 20567598-3 2010 Here, we report the identification of the 5-lipoxygenase inhibitors, NDGA, AA861, and MK886, as potent blockers of the TRPM7 channel. MK-886 86-91 transient receptor potential cation channel subfamily M member 7 Homo sapiens 119-124 30819230-10 2019 Similar to that of TRPM7 silencing, treatment with MK886, a potent 5-lipoxygenase inhibitor to reduce TRPM7 expression, and/or BAPTA-AM, an intracellular calcium chelator, significantly mitigated the Epidermal growth factor (EGF) or Insulin-like growth factors (IGF)-stimulated migration, invasion, and the EMT in ovarian cancer cells by decreasing the levels of intracellular calcium [Ca2+]i. MK-886 51-56 transient receptor potential cation channel subfamily M member 7 Homo sapiens 102-107