PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16817014-6 2006 Following NAC-MK886 treatment, there was a significant increase in caspase-3 activity, and a decrease in mitochondrial transmembrane potential compared to MK886 alone. MK-886 14-19 caspase 3 Homo sapiens 67-76 20061081-7 2010 MK886 (5-LOX activating protein inhibitor) mediated the induction of apoptosis by elevation of caspase-3 and Bax/Bcl2 ratio. MK-886 0-5 caspase 3 Homo sapiens 95-104 14675240-10 2004 Specific caspase-3 inhibitors partially blocked MK-886-induced apoptosis. MK-886 48-54 caspase 3 Homo sapiens 9-18