PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34358551-0	2021	The anti-diabetic drug trelagliptin induces vasodilation via activation of Kv channels and SERCA pumps.	trelagliptin	23-35	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3	Homo sapiens	91-96	
34358551-7	2021	Furthermore, sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump inhibitors also significantly attenuated the vasodilatory effect of trelagliptin.	trelagliptin	134-146	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3	Homo sapiens	13-52	
34358551-7	2021	Furthermore, sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump inhibitors also significantly attenuated the vasodilatory effect of trelagliptin.	trelagliptin	134-146	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3	Homo sapiens	54-59	
34358551-9	2021	SIGNIFICANCE: From these results, we concluded that the vasodilatory effect of trelagliptin was associated with the activation of Kv channels (primary the Kv7.X subtype) and SERCA pump regardless of other K+ channels, Ca2+ channels, cAMP/PKA-related or cGMP/PKG-related signaling pathways, and the endothelium.	trelagliptin	79-91	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3	Homo sapiens	174-179