PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26611369-1 2016 A novel bio-analytical method has been devised based on the change in catalytic activity of acetylcholinesterase (AChE) enzyme induced by captan, carbosulfan, 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and pentachlorophenol (PCP) for the investigation of inhibition efficiency and sensitivity using Pt/ZnO/AChE/Chitosan bioelectrode. Polychlorinated Dibenzodioxins 159-191 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-112 26611369-1 2016 A novel bio-analytical method has been devised based on the change in catalytic activity of acetylcholinesterase (AChE) enzyme induced by captan, carbosulfan, 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and pentachlorophenol (PCP) for the investigation of inhibition efficiency and sensitivity using Pt/ZnO/AChE/Chitosan bioelectrode. Polychlorinated Dibenzodioxins 159-191 acetylcholinesterase (Cartwright blood group) Homo sapiens 114-118 26611369-1 2016 A novel bio-analytical method has been devised based on the change in catalytic activity of acetylcholinesterase (AChE) enzyme induced by captan, carbosulfan, 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and pentachlorophenol (PCP) for the investigation of inhibition efficiency and sensitivity using Pt/ZnO/AChE/Chitosan bioelectrode. Polychlorinated Dibenzodioxins 159-191 acetylcholinesterase (Cartwright blood group) Homo sapiens 303-307 26611369-1 2016 A novel bio-analytical method has been devised based on the change in catalytic activity of acetylcholinesterase (AChE) enzyme induced by captan, carbosulfan, 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and pentachlorophenol (PCP) for the investigation of inhibition efficiency and sensitivity using Pt/ZnO/AChE/Chitosan bioelectrode. Polychlorinated Dibenzodioxins 193-197 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-112 26611369-1 2016 A novel bio-analytical method has been devised based on the change in catalytic activity of acetylcholinesterase (AChE) enzyme induced by captan, carbosulfan, 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and pentachlorophenol (PCP) for the investigation of inhibition efficiency and sensitivity using Pt/ZnO/AChE/Chitosan bioelectrode. Polychlorinated Dibenzodioxins 193-197 acetylcholinesterase (Cartwright blood group) Homo sapiens 114-118 26611369-1 2016 A novel bio-analytical method has been devised based on the change in catalytic activity of acetylcholinesterase (AChE) enzyme induced by captan, carbosulfan, 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and pentachlorophenol (PCP) for the investigation of inhibition efficiency and sensitivity using Pt/ZnO/AChE/Chitosan bioelectrode. Polychlorinated Dibenzodioxins 193-197 acetylcholinesterase (Cartwright blood group) Homo sapiens 303-307 26611369-4 2016 The maximum inhibition of AChE enzyme by captan was about 100 %, which was much higher than that of TCDD (72.7 %), PCP (68.1 %) and carbosulfan (47.7 %). Polychlorinated Dibenzodioxins 100-104 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-30 23426015-4 2013 OBJECTIVES: We investigated the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on acetylcholinesterase (AChE), a key enzyme in cholinergic neurotransmission. Polychlorinated Dibenzodioxins 42-77 acetylcholinesterase (Cartwright blood group) Homo sapiens 88-108 24243026-3 2014 Our previous study showed that 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) suppressed neuronal AChE enzymatic activity via transcriptional downregulations mediated by aryl hydrocarbon receptor. Polychlorinated Dibenzodioxins 31-66 acetylcholinesterase (Cartwright blood group) Homo sapiens 102-106 24243026-3 2014 Our previous study showed that 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) suppressed neuronal AChE enzymatic activity via transcriptional downregulations mediated by aryl hydrocarbon receptor. Polychlorinated Dibenzodioxins 68-80 acetylcholinesterase (Cartwright blood group) Homo sapiens 102-106 23426015-4 2013 OBJECTIVES: We investigated the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on acetylcholinesterase (AChE), a key enzyme in cholinergic neurotransmission. Polychlorinated Dibenzodioxins 42-77 acetylcholinesterase (Cartwright blood group) Homo sapiens 110-114 23426015-4 2013 OBJECTIVES: We investigated the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on acetylcholinesterase (AChE), a key enzyme in cholinergic neurotransmission. Polychlorinated Dibenzodioxins 79-83 acetylcholinesterase (Cartwright blood group) Homo sapiens 88-108 23426015-6 2013 RESULTS: We consistently found a significant decrease in enzymatic activity of AChE in cultured neurons treated with TCDD. Polychlorinated Dibenzodioxins 117-121 acetylcholinesterase (Cartwright blood group) Homo sapiens 79-83 23426015-8 2013 The addition of CH223191, an inhibitor of the aryl hydrocarbon receptor (AhR)-dependent pathway, counteracted the TCDD-induced suppression of AChE, suggesting involvement of the AhR-dependent pathway. Polychlorinated Dibenzodioxins 114-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 142-146 12082257-11 2002 The activity of three enzymes was measured (acetylcholinesterase - Ache, dehydrogenase glucoso-6-phosphate - G-6-PD and gluthatione reductase - GR) for both bfl and TCDD-treated RBC. Polychlorinated Dibenzodioxins 165-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 44-64 12082257-11 2002 The activity of three enzymes was measured (acetylcholinesterase - Ache, dehydrogenase glucoso-6-phosphate - G-6-PD and gluthatione reductase - GR) for both bfl and TCDD-treated RBC. Polychlorinated Dibenzodioxins 165-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 67-71 33317809-0 2021 Corrigendum to "Effects of astrocyte conditioned medium on neuronal AChE expression upon 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure" [Chem. Polychlorinated Dibenzodioxins 89-124 acetylcholinesterase (Cartwright blood group) Homo sapiens 68-72 31152735-2 2019 Emerging evidence has shown that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a typical persistent organic pollutant, suppressed neuronal AChE activity via dysregulation of different biosynthesis processes in human and rat neuronal cells. Polychlorinated Dibenzodioxins 33-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 137-141 31152735-2 2019 Emerging evidence has shown that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a typical persistent organic pollutant, suppressed neuronal AChE activity via dysregulation of different biosynthesis processes in human and rat neuronal cells. Polychlorinated Dibenzodioxins 70-74 acetylcholinesterase (Cartwright blood group) Homo sapiens 137-141 31152735-4 2019 As a known target cell of TCDD, the astrocyte might be involved in TCDD effects on neuronal AChE. Polychlorinated Dibenzodioxins 26-30 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-96 31152735-4 2019 As a known target cell of TCDD, the astrocyte might be involved in TCDD effects on neuronal AChE. Polychlorinated Dibenzodioxins 67-71 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-96 31152735-6 2019 The enzymatic activity of AChE was generally decreased in cultured cortical neurons upon direct treatment with TCDD (0.003-0.01 nM). Polychlorinated Dibenzodioxins 111-115 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-30 31152735-8 2019 Compared with effects of treatment with ACM plus TCDD (ACMT), a significant differential effect on AChE activity was found in the TACM group in response to TCDD treatment specifically in immature neurons, suggesting the presence of a TCDD-specific active component derived from the astrocyte. Polychlorinated Dibenzodioxins 156-160 acetylcholinesterase (Cartwright blood group) Homo sapiens 99-103 31152735-10 2019 These data indicate that the astrocyte might play a protective role in TCDD-induced alterations of neuronal AChE in certain stages of differentiation. Polychlorinated Dibenzodioxins 71-75 acetylcholinesterase (Cartwright blood group) Homo sapiens 108-112 31152735-0 2019 Effects of astrocyte conditioned medium on neuronal AChE expression upon 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Polychlorinated Dibenzodioxins 73-108 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-56