PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21244636-2 2011 Hymenialdisine potently inhibits glycogen synthase kinase 3beta, cyclin-dependent kinase 2, and cyclin-dependent kinase 5, whereas dibromocantharelline only displays a significant inhibitory effect toward glycogen synthase kinase 3beta (IC(50) = 3 mumol). hymenialdisine 0-14 glycogen synthase kinase 3 beta Homo sapiens 33-90 21244636-2 2011 Hymenialdisine potently inhibits glycogen synthase kinase 3beta, cyclin-dependent kinase 2, and cyclin-dependent kinase 5, whereas dibromocantharelline only displays a significant inhibitory effect toward glycogen synthase kinase 3beta (IC(50) = 3 mumol). hymenialdisine 0-14 glycogen synthase kinase 3 beta Homo sapiens 33-63 21244636-4 2011 The similar binding modes of hymenialdisine in complex with cyclin-dependent kinase 5 and glycogen synthase kinase 3beta are consistent with the poor selectivity of hymenialdisine toward the two kinases. hymenialdisine 29-43 glycogen synthase kinase 3 beta Homo sapiens 90-120 21244636-4 2011 The similar binding modes of hymenialdisine in complex with cyclin-dependent kinase 5 and glycogen synthase kinase 3beta are consistent with the poor selectivity of hymenialdisine toward the two kinases. hymenialdisine 165-179 glycogen synthase kinase 3 beta Homo sapiens 90-120