PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34377229-5 2021 This finding suggests that both KrasG12V and KrasG12D are required for showing higher FL118 efficacy, while the presence of KrasG13D could somehow decrease FL118 efficacy under the defined p53/APC genetic status. 7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione 156-161 APC regulator of WNT signaling pathway Homo sapiens 193-196 34377229-10 2021 These findings would be useful for predicting FL118 sensitivity to patients" CRC tumors with the defined Kras mutation subtypes under the defined p53/APC genetic status. 7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione 46-51 APC regulator of WNT signaling pathway Homo sapiens 150-153