PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31404613-7	2019	Mechanistically, the metabolic change and anti-cancer effect by GSK-3beta inhibition was achieved mainly through activation of adenosine 5"-monophosphate (AMP)-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) signaling, which negatively affected glycolysis and cell proliferation.	adenosine 5"-monophosphate	127-153	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	186-190	
30666163-10	2019	Furthermore, metformin significantly activated Adenosine 5"-monophosphate (AMP)-activated protein kinase (AMPK) and its downstream glycogen synthase kinase 3beta (GSK-3beta), block the expression of AMPK, and GSK-3beta with siRNA partially reversed metformin-induced cytotoxicity and restored the expression of c-FLIPL in lung cancer cells.	adenosine 5"-monophosphate	47-73	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	106-110