PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30903350-9	2019	Our results showed that thymol markedly inhibited the production of MPO and TNF-alpha in the colon tissue of the acetic acid-induced group.	Acetic Acid	113-124	tumor necrosis factor	Rattus norvegicus	76-85	
30263277-6	2016	BF-RBEE also inhibited acetic acid-mediated increases in mRNA levels of nitric oxide synthase, interleukin-1beta, and tumor necrosis factor-alpha.	Acetic Acid	23-34	tumor necrosis factor	Rattus norvegicus	118-145	
26062761-13	2015	Administration of acetic acid resulted in increased levels of tumor necrosis factor-alpha, interleukin-1beta, interleukin-6, total nitrite/nitrate levels and nitric oxide synthase activity.	Acetic Acid	18-29	tumor necrosis factor	Rattus norvegicus	62-89	
19281808-3	2009	Chronic gastric ulcer induced in rats by intraluminal application of acetic acid resulted in elevation of proinflammatory cytokines gene expression, such as, TNF-alpha (Tumor Necrosis Factor-alpha), IL-1beta (Interleukin-1beta) and the protein levels of nuclear p65 subunit of NF-kappaB (Nuclear Factor-kappaB) but decreased levels of PPAR-gamma gene expression.	Acetic Acid	69-80	tumor necrosis factor	Rattus norvegicus	158-167	
19281808-3	2009	Chronic gastric ulcer induced in rats by intraluminal application of acetic acid resulted in elevation of proinflammatory cytokines gene expression, such as, TNF-alpha (Tumor Necrosis Factor-alpha), IL-1beta (Interleukin-1beta) and the protein levels of nuclear p65 subunit of NF-kappaB (Nuclear Factor-kappaB) but decreased levels of PPAR-gamma gene expression.	Acetic Acid	69-80	tumor necrosis factor	Rattus norvegicus	169-196	
16610053-15	2006	CONCLUSION: Administration of 20% acetic acid can induce gastric inflammation, increase leukocyte adherence in postcapillary venule and TNF-alpha level and reduce IL-10 level.	Acetic Acid	34-45	tumor necrosis factor	Rattus norvegicus	136-145	
15652655-13	2005	Serum LDH and TNF-alpha levels were also elevated in the acetic acid-induced colitis group as compared to control group, while this increase was significantly decreased by OT treatment.	Acetic Acid	57-68	tumor necrosis factor	Rattus norvegicus	14-23	
35561078-3	2022	suppress acetic acid-induced ulcerative colitis in rats by reducing TNF-alpha and interleukin-6, oxidative stress parameters and improving mucosal protection.	Acetic Acid	9-20	tumor necrosis factor	Rattus norvegicus	68-77	
32426537-8	2020	Exposure of rat colon to acetic acid significantly altered (p < 0.05) serum levels of tumour necrosis factor-alpha (TNF-alpha), interleukin - 6 (IL-6), nitric oxide (NO), lipid peroxidation product (malondialdehyde or MDA), reduced glutathione (GSH); and activities of superoxide dismutase (SOD) and catalase (CAT).	Acetic Acid	25-36	tumor necrosis factor	Rattus norvegicus	116-125	
32090060-0	2020	Acetic Acid-Induced Ulcerative Colitis in Sprague Dawley Rats Is Suppressed by Hydroethanolic Extract of Cordia vignei Leaves through Reduced Serum Levels of TNF-alpha and IL-6.	Acetic Acid	0-11	tumor necrosis factor	Rattus norvegicus	158-167	
21644797-6	2011	In acetic acid ulcer, promotion of ulcer-healing effects was partly due to attenuation of the elevated levels of the inflammatory cytokines TNF-alpha, interferon-gamma, and interleukins-4 and -6.	Acetic Acid	3-14	tumor necrosis factor	Rattus norvegicus	140-149	
34745922-11	2021	persicum essential oil</compound-id> (200 and 400 mg/kg) decreased the activity of MPO and TNF-alpha in the colon tissue of rats compared with the acetic acid group.	Acetic Acid	147-158	tumor necrosis factor	Rattus norvegicus	91-100	
33802553-0	2021	Role of Oxidative Stress and Inflammatory Cytokines (TNF-alpha and IL-6) in Acetic Acid-Induced Ulcerative Colitis in Rats: Ameliorated by Otostegia fruticosa.	Acetic Acid	76-87	tumor necrosis factor	Rattus norvegicus	53-62