PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35563082-2	2022	Acetic acid activates AMP-activated protein kinase (AMPK), which plays a key role in the regulation of whole-body energy by phosphorylating key metabolic enzymes in both biosynthetic and oxidative pathways and stimulates gene expression associated with slow-twitch fibers and mitochondria in skeletal muscle cells.	Acetic Acid	0-11	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	22-50	
35563082-2	2022	Acetic acid activates AMP-activated protein kinase (AMPK), which plays a key role in the regulation of whole-body energy by phosphorylating key metabolic enzymes in both biosynthetic and oxidative pathways and stimulates gene expression associated with slow-twitch fibers and mitochondria in skeletal muscle cells.	Acetic Acid	0-11	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	52-56	
35563082-3	2022	In this study, we investigate whether long-term supplementation with acetic acid improves age-related changes in the skeletal muscle of aging rats in association with the activation of AMPK.	Acetic Acid	69-80	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	185-189	
35563082-5	2022	Long-term supplementation with acetic acid decreased the expression of atrophy-related genes, such as atrogin-1, muscle RING-finger protein-1 (MuRF1), and transforming growth factor beta (TGF-beta), activated AMPK, and affected the proliferation of mitochondria and type I fiber-related molecules in muscles.	Acetic Acid	31-42	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	209-213	
34002329-0	2021	Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFkappaB/AMPK/NLRP3 axis.	Acetic Acid	47-58	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	105-109	
27348124-2	2016	Administered acetic acid led to increased phosphorylation of AMP-activated protein kinase (AMPK) in both liver and skeletal muscle cells, and increased transcripts of myoglobin and glucose transporter 4 (GLUT4) genes in skeletal muscle of the rats.	Acetic Acid	13-24	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	61-89	
27348124-2	2016	Administered acetic acid led to increased phosphorylation of AMP-activated protein kinase (AMPK) in both liver and skeletal muscle cells, and increased transcripts of myoglobin and glucose transporter 4 (GLUT4) genes in skeletal muscle of the rats.	Acetic Acid	13-24	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	91-95	
27348124-5	2016	Acetic acid added to culture medium was taken up rapidly by L6 cells, and AMPK was phosphorylated upon treatment with acetic acid.	Acetic Acid	0-11	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	74-78	
27348124-5	2016	Acetic acid added to culture medium was taken up rapidly by L6 cells, and AMPK was phosphorylated upon treatment with acetic acid.	Acetic Acid	118-129	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	74-78	
27348124-9	2016	These results indicate that acetic acid enhances glucose uptake and fatty acid metabolism through the activation of AMPK, and increases expression of GLUT4 and myoglobin.	Acetic Acid	28-39	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	116-120	
16630552-0	2006	Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice.	Acetic Acid	0-11	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	30-34	
16630552-6	2006	These results indicate that the hypoglycemic effect of AcOH might be due to activation of AMPK in the liver.	Acetic Acid	55-59	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	90-94