PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16630552-0 2006 Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. Acetic Acid 0-11 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 30-34 16630552-6 2006 These results indicate that the hypoglycemic effect of AcOH might be due to activation of AMPK in the liver. Acetic Acid 55-59 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 90-94 35563082-2 2022 Acetic acid activates AMP-activated protein kinase (AMPK), which plays a key role in the regulation of whole-body energy by phosphorylating key metabolic enzymes in both biosynthetic and oxidative pathways and stimulates gene expression associated with slow-twitch fibers and mitochondria in skeletal muscle cells. Acetic Acid 0-11 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 22-50 35563082-2 2022 Acetic acid activates AMP-activated protein kinase (AMPK), which plays a key role in the regulation of whole-body energy by phosphorylating key metabolic enzymes in both biosynthetic and oxidative pathways and stimulates gene expression associated with slow-twitch fibers and mitochondria in skeletal muscle cells. Acetic Acid 0-11 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 52-56 35563082-3 2022 In this study, we investigate whether long-term supplementation with acetic acid improves age-related changes in the skeletal muscle of aging rats in association with the activation of AMPK. Acetic Acid 69-80 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 185-189 35563082-5 2022 Long-term supplementation with acetic acid decreased the expression of atrophy-related genes, such as atrogin-1, muscle RING-finger protein-1 (MuRF1), and transforming growth factor beta (TGF-beta), activated AMPK, and affected the proliferation of mitochondria and type I fiber-related molecules in muscles. Acetic Acid 31-42 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 209-213 34002329-0 2021 Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFkappaB/AMPK/NLRP3 axis. Acetic Acid 47-58 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 105-109 27348124-2 2016 Administered acetic acid led to increased phosphorylation of AMP-activated protein kinase (AMPK) in both liver and skeletal muscle cells, and increased transcripts of myoglobin and glucose transporter 4 (GLUT4) genes in skeletal muscle of the rats. Acetic Acid 13-24 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 61-89 27348124-2 2016 Administered acetic acid led to increased phosphorylation of AMP-activated protein kinase (AMPK) in both liver and skeletal muscle cells, and increased transcripts of myoglobin and glucose transporter 4 (GLUT4) genes in skeletal muscle of the rats. Acetic Acid 13-24 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 91-95 27348124-5 2016 Acetic acid added to culture medium was taken up rapidly by L6 cells, and AMPK was phosphorylated upon treatment with acetic acid. Acetic Acid 0-11 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 74-78 27348124-5 2016 Acetic acid added to culture medium was taken up rapidly by L6 cells, and AMPK was phosphorylated upon treatment with acetic acid. Acetic Acid 118-129 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 74-78 27348124-9 2016 These results indicate that acetic acid enhances glucose uptake and fatty acid metabolism through the activation of AMPK, and increases expression of GLUT4 and myoglobin. Acetic Acid 28-39 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 116-120