PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24930757-0	2014	Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.	ilimaquinone	0-12	TNF superfamily member 10	Homo sapiens	90-95	
24930757-4	2014	In the present study, we investigated the molecular mechanisms by which ilimaquinone isolated from a sea sponge sensitizes human colon cancer cells to TRAIL.	ilimaquinone	72-84	TNF superfamily member 10	Homo sapiens	151-156	
24930757-5	2014	Ilimaquinone pretreatment significantly enhanced TRAIL-induced apoptosis in HCT 116 cells and sensitized colon cancer cells to TRAIL-induced apoptosis through increased caspase-8, -3 activation, PARP cleavage, and DNA damage.	ilimaquinone	0-12	TNF superfamily member 10	Homo sapiens	49-54	
24930757-5	2014	Ilimaquinone pretreatment significantly enhanced TRAIL-induced apoptosis in HCT 116 cells and sensitized colon cancer cells to TRAIL-induced apoptosis through increased caspase-8, -3 activation, PARP cleavage, and DNA damage.	ilimaquinone	0-12	TNF superfamily member 10	Homo sapiens	127-132	
24930757-10	2014	These results demonstrate that ilimaquinone enhanced the sensitivity of human colon cancer cells to TRAIL-induced apoptosis through ROS-ERK/p38 MAPK-CHOP-mediated up-regulation of DR4 and DR5 expression, suggesting that ilimaquinone could be developed into an adjuvant chemotherapeutic drug.	ilimaquinone	31-43	TNF superfamily member 10	Homo sapiens	100-105	
24930757-10	2014	These results demonstrate that ilimaquinone enhanced the sensitivity of human colon cancer cells to TRAIL-induced apoptosis through ROS-ERK/p38 MAPK-CHOP-mediated up-regulation of DR4 and DR5 expression, suggesting that ilimaquinone could be developed into an adjuvant chemotherapeutic drug.	ilimaquinone	220-232	TNF superfamily member 10	Homo sapiens	100-105