PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15663890-4	2005	The effects of Ac-YVAD-CHO on QA-induced caspase-1 activity, internucleosomal DNA fragmentation, IkappaB-alpha degradation, NF-kappaB, and AP-1 activation, and increases in p53 protein levels were measured with enzyme assays, agarose gel electrophoresis, electrophoresis mobility shift assays, and Western blot analysis.	Quinolinic Acid	30-32	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	173-176	
20092569-5	2009	QA induced increases in the expression of p53, PUMA, Bax and a decrease in Bcl-2.	Quinolinic Acid	0-2	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	42-45	
15663890-0	2005	Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis in rat striatum.	Quinolinic Acid	43-58	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	80-83	
15663890-6	2005	Ac-YVAD-CHO inhibited QA-induced increases in caspase-1 activity and p53 protein levels, but had no effect on QA-induced IkappaB-alpha degradation, NF-kappaB or AP-1 activation.	Quinolinic Acid	22-24	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	69-72	
15663890-7	2005	CONCLUSION: Caspase-1 is involved in QA-induced p53 upregulation but not IkappaB-alpha degradation.	Quinolinic Acid	37-39	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	48-51	
10234031-8	1999	NF-kappaB SN50 significantly inhibited the QA-induced elevation in levels of c-Myc and p53 mRNA and protein.	Quinolinic Acid	43-45	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	87-90	
8895882-0	1996	Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation.	Quinolinic Acid	37-52	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	75-78	
8895882-0	1996	Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation.	Quinolinic Acid	37-52	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	109-112	
8895882-5	1996	Here we report that excitotoxic lesion of rat brain with the N-methyl-D-aspartate receptor agonist, quinolinic acid, induces expression of p53 messenger RNA and protein in brain regions showing delayed DNA fragmentation and that expression of p53 messenger RNA precedes DNA damage detected by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labelling.	Quinolinic Acid	100-115	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	139-142	
8895882-5	1996	Here we report that excitotoxic lesion of rat brain with the N-methyl-D-aspartate receptor agonist, quinolinic acid, induces expression of p53 messenger RNA and protein in brain regions showing delayed DNA fragmentation and that expression of p53 messenger RNA precedes DNA damage detected by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labelling.	Quinolinic Acid	100-115	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	243-246