PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7969907-0	1994	Intrastriatal infusion of nerve growth factor after quinolinic acid prevents reduction of cellular expression of choline acetyltransferase messenger RNA and trkA messenger RNA, but not glutamate decarboxylase messenger RNA.	Quinolinic Acid	52-67	nerve growth factor	Rattus norvegicus	26-45	
21551853-8	1996	In a final study, we examined striatal tissue from rats who had been protected from striatal quinolinic acid neurotoxicity by administration of NGF.	Quinolinic Acid	93-108	nerve growth factor	Rattus norvegicus	144-147	
7589325-7	1995	QUIN and QUIS increased NGF protein and these effects were maximal with lesions in 21-day-old rats.	Quinolinic Acid	0-4	nerve growth factor	Rattus norvegicus	24-27	
7589325-12	1995	QUIN induced an increase in NGF levels 1 day after lesion.	Quinolinic Acid	0-4	nerve growth factor	Rattus norvegicus	28-31	
7854071-0	1994	Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid.	Quinolinic Acid	180-195	nerve growth factor	Rattus norvegicus	45-64	
7854071-3	1994	As in other excitatory paradigms, nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) mRNA levels increased dramatically and transiently in dentate gyrus after the administration of 120 nmol of QUIN to the left hippocampus.	Quinolinic Acid	213-217	nerve growth factor	Rattus norvegicus	34-53	
7854071-3	1994	As in other excitatory paradigms, nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) mRNA levels increased dramatically and transiently in dentate gyrus after the administration of 120 nmol of QUIN to the left hippocampus.	Quinolinic Acid	213-217	nerve growth factor	Rattus norvegicus	55-58	
7854071-6	1994	A very different pattern of expression of NTFs was found locally: (a) upregulation of NGF and BDNF mRNAs expression was prevented in a spherical region of 1-2 mm diameter around the injection site, (b) a delayed increase in NT3 mRNA levels, beginning at 12 h and lasting for at least 4 days after the administration of QUIN, was found in the same region, in cell layers showing neurodegeneration.	Quinolinic Acid	319-323	nerve growth factor	Rattus norvegicus	86-89	
7854071-12	1994	Finally, our pharmacological data, (i) show that the upregulation of NGF and BDNF mRNAs, indirectly induced by QUIN, is not mediated by AMPA receptors, and (ii) suggest other effects for QUIN, apart from the stimulation of NMDA receptors.	Quinolinic Acid	111-115	nerve growth factor	Rattus norvegicus	69-72	
7854071-12	1994	Finally, our pharmacological data, (i) show that the upregulation of NGF and BDNF mRNAs, indirectly induced by QUIN, is not mediated by AMPA receptors, and (ii) suggest other effects for QUIN, apart from the stimulation of NMDA receptors.	Quinolinic Acid	187-191	nerve growth factor	Rattus norvegicus	69-72	
7969907-8	1994	Optical density measurements of the entire striatum on autoradiographs of brain sections from quinolinic acid-lesioned animals revealed a reduction of the glutamate decarboxylase messenger RNA-specific hybridization signal, which was unaltered by infusion of nerve growth factor or control protein.	Quinolinic Acid	94-109	nerve growth factor	Rattus norvegicus	259-278	
7969907-9	1994	Our findings strongly suggest that in both the intact and the quinolinic acid-lesioned adult rat striatum, nerve growth factor action is confined to trk A-expressing cholinergic neurons.	Quinolinic Acid	62-77	nerve growth factor	Rattus norvegicus	107-126	
10069578-2	1998	Up-regulation of NGF expression was observed at 24 h after intrastriatal quinolinate injection, an N-methyl-D-aspartate receptor agonist, and this increase was maintained up to 7 days after lesion.	Quinolinic Acid	73-84	nerve growth factor	Rattus norvegicus	17-20	
8075815-0	1994	Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum.	Quinolinic Acid	91-106	nerve growth factor	Rattus norvegicus	0-19	
12053462-4	2002	The other two groups of animals were pretreated immediately before QA application with NGF and FGF, respectively.	Quinolinic Acid	67-69	nerve growth factor	Rattus norvegicus	87-90	
11490092-4	2000	Results: NGF prevented the QA-induced decline in glutathione reductase activity and GSH content.	Quinolinic Acid	27-29	nerve growth factor	Rattus norvegicus	9-12