PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11038244-7 2000 QA-induced IkappaB-alpha degradation and NF-kappaB activation were not affected by the proteasome inhibitor MG-132 (1-4 microg). Quinolinic Acid 0-2 NFKB inhibitor alpha Rattus norvegicus 11-24 10719066-4 2000 The results indicated that the QA-induced degradation of IkappaB-alpha is almost totally mediated by a caspase-3-dependent mechanism, while KA-induced IkappaB-alpha degradation is only partially dependent on caspase-3. Quinolinic Acid 31-33 NFKB inhibitor alpha Rattus norvegicus 57-70 9889320-6 1999 Western blot analysis and electrophoresis mobility shift assay further revealed that the free radical scavenger (300 and 600 mg/kg) blunted the QA-induced degradation of IkappaBalpha (increased IkappaBalpha levels from about 15% to 33 and 62% of control, respectively; p<0.01) as well as the ensuing activation of NF-kappaB by 25 to 34%, respectively (p<0. Quinolinic Acid 144-146 NFKB inhibitor alpha Rattus norvegicus 170-182 9889320-6 1999 Western blot analysis and electrophoresis mobility shift assay further revealed that the free radical scavenger (300 and 600 mg/kg) blunted the QA-induced degradation of IkappaBalpha (increased IkappaBalpha levels from about 15% to 33 and 62% of control, respectively; p<0.01) as well as the ensuing activation of NF-kappaB by 25 to 34%, respectively (p<0. Quinolinic Acid 144-146 NFKB inhibitor alpha Rattus norvegicus 194-206 24073275-9 2013 QA-induced degradation of IkappaB-alpha, NF-kappaB nuclear translocation, up-regulation of NF-kappaB responsive gene TP53, and activation of caspase-3 was strongly inhibited by Z-FF-FMK or NaphthaCHO. Quinolinic Acid 0-2 NFKB inhibitor alpha Rattus norvegicus 26-39 16206188-9 2005 Se reduced the QUIN-induced decrease in IkappaB-alpha expression, evidencing a reduction in its cytosolic degradation. Quinolinic Acid 15-19 NFKB inhibitor alpha Rattus norvegicus 40-53