PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19051152-3 2008 The high-profile withdrawal of drugs such as mibefradil from the market because of unfavorable drug-drug interaction profiles has focused efforts on screening for cytochrome P450 (CYP)-mediated drug interactions early in the discovery paradigm and on predicting the impact of inhibition on the in vivo situation. Mibefradil 45-55 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 163-178 19051152-3 2008 The high-profile withdrawal of drugs such as mibefradil from the market because of unfavorable drug-drug interaction profiles has focused efforts on screening for cytochrome P450 (CYP)-mediated drug interactions early in the discovery paradigm and on predicting the impact of inhibition on the in vivo situation. Mibefradil 45-55 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 180-183