PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25109503-8 2014 RESULTS: Compared with normal control, TGF-beta1 secretion was significantly increased in asthmatic ASMCs; meanwhile, TGF-beta1 promoted ASMCs proliferation (P < 0.05). asmcs 100-105 transforming growth factor, beta 1 Rattus norvegicus 39-48 11348874-9 2001 In contrast, the growth response of decorin-overexpressing ASMCs to TGF-beta1, as well as the expression of TGF-beta1-responsive genes, such as plasminogen activator inhibitor-1 and versican (an extracellular matrix proteoglycan), was diminished. asmcs 59-64 transforming growth factor, beta 1 Rattus norvegicus 68-77 11348874-10 2001 These results indicate that decorin selectively inhibits the responsiveness of rat ASMCs to TGF-beta1 and suggests that the induction of constitutive decorin overexpression by ASMCs in vivo may have therapeutic value in the inhibition of TGF-beta1-mediated effects on the development of atherosclerotic lesions. asmcs 83-88 transforming growth factor, beta 1 Rattus norvegicus 92-101 29949788-13 2018 CONCLUSION: The results of our study suggest that miR-142 inhibits proliferation and promotes apoptosis in ASMCs during airway remodeling in asthmatic rats by inhibiting TGF-beta expression via a mechanism involving the EGFR signaling pathway. asmcs 107-112 transforming growth factor, beta 1 Rattus norvegicus 170-178 30132829-7 2018 Preincubation of rat ASMCs with pioglitazone, a PPAR-gamma activator, blocked TGF-beta1-induced activation of Smad2/3 and its downstream targets changes of miR-21, PTEN, Akt, FOXO1, and cyclin D1, resulting in the inhibition of rat ASMC proliferation. asmcs 21-26 transforming growth factor, beta 1 Rattus norvegicus 78-87 22270542-2 2012 Urotensin II (UII) and transforming growth factor (TGF)-beta are potent mitogens for ASMCs proliferation. asmcs 85-90 transforming growth factor, beta 1 Rattus norvegicus 51-60 22270542-3 2012 The study was aimed to determine whether UII-upregulated TGF-beta-mediated ASMCs proliferation and extracellular signal-regulated kinase (ERK) was required for such an effect. asmcs 75-80 transforming growth factor, beta 1 Rattus norvegicus 57-65 22270542-7 2012 In vitro experiments were conducted to determine the direct effect of UII on TGF-beta1 expression by ASMCs. asmcs 101-106 transforming growth factor, beta 1 Rattus norvegicus 77-86 22270542-10 2012 In vitro study on ASMCs further revealed that UII may render its effect on ASMCs cells through the upregulation of TGF-beta1. asmcs 18-23 transforming growth factor, beta 1 Rattus norvegicus 115-124 22270542-12 2012 The current study provides new evidence that UII is involved in the TGF-beta mediated mitogenic effect on ASMCs. asmcs 106-111 transforming growth factor, beta 1 Rattus norvegicus 68-76