PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21410432-4	2011	Here, we present crystal structures of the CARM1 catalytic domain in complex with cofactors [SAH (S-adenosyl-L-homocysteine) or SNF (sinefungin)] and indole or pyazole inhibitors.	S-Adenosylhomocysteine	98-123	acyl-CoA synthetase medium chain family member 3	Homo sapiens	93-96	
20864509-1	2010	S-adenosyl-(L)-homocysteine (SAH) riboswitches are regulatory elements found in bacterial mRNAs that up-regulate genes involved in the S-adenosyl-(L)-methionine (SAM) regeneration cycle.	S-Adenosylhomocysteine	0-27	acyl-CoA synthetase medium chain family member 3	Homo sapiens	29-32	
34783058-8	2022	S-adenosylmethionine//S-adenosylhomocysteine (SAM/SAH) levels were evaluated by enzyme-linked immunosorbent assay.	S-Adenosylhomocysteine	22-44	acyl-CoA synthetase medium chain family member 3	Homo sapiens	46-53	
17004132-1	2006	Homocysteine is a sulfur-containing, nonproteinogenic, neurotoxic amino acid biosynthesized during methyl cycles after demethylation of S-adenosylmethionine (SAM) to S-adenosylhomocysteine (SAH) and subsequent hydrolysis of SAH into homocysteine and adenosine.	S-Adenosylhomocysteine	166-188	acyl-CoA synthetase medium chain family member 3	Homo sapiens	190-193	
12859184-3	2003	Unlike most SAM-dependent methyltransferases, GNMT has a relatively high value and is weakly inhibited by the product S-adenosyl-l-homocysteine (SAH).	S-Adenosylhomocysteine	118-143	acyl-CoA synthetase medium chain family member 3	Homo sapiens	145-148	
33020707-4	2020	In the present study, molecular recognition between the two natural nucleoside analogs (S-adenosyl-L-homocysteine (SAH) and sinefungin (SFG)) and the SARS-CoV-2 nsp16/nsp10/m7GpppAC5 was studied using all-atom molecular dynamics simulations and free energy calculations based on MM/GBSA and WaterSwap approaches.	S-Adenosylhomocysteine	88-113	acyl-CoA synthetase medium chain family member 3	Homo sapiens	115-118	
33993848-7	2022	Our study uncovers a new axis of SAH-AHCYL1-PIK3C3, which senses the intracellular level of SAH to inhibit autophagy in an MTORC1-independent manner.Abbreviations: ADOX: adenosine dialdehyde; AHCY: adenosylhomocysteinase; AHCYL1: adenosylhomocysteinase like 1; cLEU: cycloleucine; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PtdIns3P: phosphatidylinositol-3-phosphate; SAH: S-adenosyl-l-homocysteine; SAM: S-adenosyl-l-methionine.	S-Adenosylhomocysteine	394-419	acyl-CoA synthetase medium chain family member 3	Homo sapiens	33-36	
33993848-7	2022	Our study uncovers a new axis of SAH-AHCYL1-PIK3C3, which senses the intracellular level of SAH to inhibit autophagy in an MTORC1-independent manner.Abbreviations: ADOX: adenosine dialdehyde; AHCY: adenosylhomocysteinase; AHCYL1: adenosylhomocysteinase like 1; cLEU: cycloleucine; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PtdIns3P: phosphatidylinositol-3-phosphate; SAH: S-adenosyl-l-homocysteine; SAM: S-adenosyl-l-methionine.	S-Adenosylhomocysteine	394-419	acyl-CoA synthetase medium chain family member 3	Homo sapiens	92-95	
33993848-7	2022	Our study uncovers a new axis of SAH-AHCYL1-PIK3C3, which senses the intracellular level of SAH to inhibit autophagy in an MTORC1-independent manner.Abbreviations: ADOX: adenosine dialdehyde; AHCY: adenosylhomocysteinase; AHCYL1: adenosylhomocysteinase like 1; cLEU: cycloleucine; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PtdIns3P: phosphatidylinositol-3-phosphate; SAH: S-adenosyl-l-homocysteine; SAM: S-adenosyl-l-methionine.	S-Adenosylhomocysteine	394-419	acyl-CoA synthetase medium chain family member 3	Homo sapiens	92-95	
6091559-3	1984	In the hydrolysis direction, the enzyme has a pH optimum of 7.5, a Km for S-adenosyl-L-homocysteine (SAH) of 6 microM, and a Vmax of 0.22 mumol min-1 mg-1.	S-Adenosylhomocysteine	74-99	acyl-CoA synthetase medium chain family member 3	Homo sapiens	101-104	
33993848-1	2022	S-adenosyl-l-homocysteine (SAH), an amino acid derivative, is a key intermediate metabolite in methionine metabolism, which is normally considered as a harmful by-product and hydrolyzed quickly once formed.	S-Adenosylhomocysteine	0-25	acyl-CoA synthetase medium chain family member 3	Homo sapiens	27-30	
27934872-6	2016	A structural analysis revealed that, despite the simultaneous presence of both substrate (sarcosine) and cofactor (S-adenosyl-L-homocysteine; SAH), the enzyme was likely crystallized in an inactive conformation, as additional structural changes are required to complete the active site assembly.	S-Adenosylhomocysteine	115-140	acyl-CoA synthetase medium chain family member 3	Homo sapiens	142-145	
29679079-2	2018	We employed molecular dynamics and Gaussian accelerated molecular dynamics techniques to investigate the structure of Zika NS5 protein with S-adenosyl-L-homocysteine (SAH) and an RNA analogue, namely 7-methylguanosine 5"-triphosphate (m7GTP).	S-Adenosylhomocysteine	140-165	acyl-CoA synthetase medium chain family member 3	Homo sapiens	167-170