PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30291293-0 2018 Ankyrin Repeat Domain 1 Overexpression is Associated with Common Resistance to Afatinib and Osimertinib in EGFR-mutant Lung Cancer. osimertinib 92-103 ankyrin repeat domain 1 Homo sapiens 0-23 30291293-6 2018 When ANKRD1 was silenced in the EGFR-TKIs-resistant cell lines, afatinib and osimertinib could induce apoptosis of the cell lines. osimertinib 77-88 ankyrin repeat domain 1 Homo sapiens 5-11 30291293-7 2018 Imatinib could inhibit ANKRD1 expression, resulting in restoration of the sensitivity to afatinib and osimertinib of EGFR-TKI-resistant cells. osimertinib 102-113 ankyrin repeat domain 1 Homo sapiens 23-29