PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32272148-0 2020 Desmoglein-2 modulates tumor progression and osimertinib drug resistance through the EGFR/Src/PAK1 pathway in lung adenocarcinoma. osimertinib 45-56 desmoglein 2 Homo sapiens 0-12 32272148-3 2020 Notably, DSG2 overexpression promoted cell proliferation and migration, and increased resistance to the EGFR tyrosine kinase inhibitor osimertinib, whereas DSG2 silencing could reverse these results. osimertinib 135-146 desmoglein 2 Homo sapiens 9-13 32272148-6 2020 Consistent with these findings, a nude mouse xenograft model using H1975 cells demonstrated that DSG2 promoted LUAD cell growth in vivo and increased osimertinib resistance. osimertinib 150-161 desmoglein 2 Homo sapiens 97-101