PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25794333-9 2015 In contradistinction to 3,4-methylenedioxymethamphetamine, which induces its toxicity through SERT and DAT, these data indicate that DAT, but not SERT, is strongly associated with the lethal toxicity produced by methylone, which did not seem to be dependent on the hyperthermic effects of methylone. methylone 212-221 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 133-136 25794333-3 2015 Methylone has been assumed to induce hyperthermic effects through inhibition of serotonin and/or dopamine transporters (SERT and DAT, respectively). methylone 0-9 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 129-132 25794333-7 2015 By contrast, only a slight diminution in the hyperthermic effects of methylone was observed in DAT KO mice, whereas a slight enhancement of these effects was observed in SERT KO mice. methylone 69-78 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 95-98 25794333-9 2015 In contradistinction to 3,4-methylenedioxymethamphetamine, which induces its toxicity through SERT and DAT, these data indicate that DAT, but not SERT, is strongly associated with the lethal toxicity produced by methylone, which did not seem to be dependent on the hyperthermic effects of methylone. methylone 289-298 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 133-136 25794333-10 2015 DAT is therefore a strong candidate molecule for interventions aimed at preventing acute neurotoxic and lethal effects of methylone. methylone 122-131 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 0-3