PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28728105-0	2017	Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis.	imidazopyridine	13-29	beta-secretase 1	Homo sapiens	91-96	
28728105-4	2017	We designed a series of imidazopyridines-based compounds bearing phthalimide moieties as inhibitors of BACE1.	imidazopyridine	24-40	beta-secretase 1	Homo sapiens	103-108	
28728105-6	2017	Evaluating the BACE1 inhibitory effects of the synthesized compounds revealed that introducing an aminocyclohexyl moiety in the imidazopyridine core resulted in a significant improvement in its BACE1 inhibitory potential.	imidazopyridine	128-143	beta-secretase 1	Homo sapiens	15-20	
28728105-6	2017	Evaluating the BACE1 inhibitory effects of the synthesized compounds revealed that introducing an aminocyclohexyl moiety in the imidazopyridine core resulted in a significant improvement in its BACE1 inhibitory potential.	imidazopyridine	128-143	beta-secretase 1	Homo sapiens	194-199	
28728105-8	2017	Molecular docking revealed that the nitrogen atom of imidazopyridines and the oxygen atom of the phenoxypropyl linker were involved in hydrogen bound interactions with Asp228 and Asp32 of BACE1 active site, respectively.	imidazopyridine	53-69	beta-secretase 1	Homo sapiens	188-193