PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27430552-8 2016 In addition, sivelestat suppressed the CLP-induced macrophage infiltration, the overproduction of pro-inflammatory mediators (tumor necrosis factor-alpha, interleukin-1beta, high-mobility group box 1 and inducible nitric oxide synthase) and serine/threonine kinase (Akt) pathway activation in the rats. sivelestat 13-23 tumor necrosis factor Rattus norvegicus 98-153 24111663-13 2014 In addition, systemic inflammation was partially suppressed with SV treatment, suppressing TNF-alpha production. sivelestat 65-67 tumor necrosis factor Rattus norvegicus 91-100 23794035-5 2013 Increasing doses of sivelestat inhibits the expression of lipase, amylase, corticosterone, IL-1beta, TNF-alpha, and nuclear factor-kappaB. sivelestat 20-30 tumor necrosis factor Rattus norvegicus 101-110 22484827-8 2012 Sivelestat or edaravone treatment also attenuated the LPS-induced production of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor alpha (TNF-alpha) in rat lungs. sivelestat 0-10 tumor necrosis factor Rattus norvegicus 130-157 22484827-8 2012 Sivelestat or edaravone treatment also attenuated the LPS-induced production of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor alpha (TNF-alpha) in rat lungs. sivelestat 0-10 tumor necrosis factor Rattus norvegicus 159-168