PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27430552-8	2016	In addition, sivelestat suppressed the CLP-induced macrophage infiltration, the overproduction of pro-inflammatory mediators (tumor necrosis factor-alpha, interleukin-1beta, high-mobility group box 1 and inducible nitric oxide synthase) and serine/threonine kinase (Akt) pathway activation in the rats.	sivelestat	13-23	tumor necrosis factor	Rattus norvegicus	98-153	
24111663-13	2014	In addition, systemic inflammation was partially suppressed with SV treatment, suppressing TNF-alpha production.	sivelestat	65-67	tumor necrosis factor	Rattus norvegicus	91-100	
23794035-5	2013	Increasing doses of sivelestat inhibits the expression of lipase, amylase, corticosterone, IL-1beta, TNF-alpha, and nuclear factor-kappaB.	sivelestat	20-30	tumor necrosis factor	Rattus norvegicus	101-110	
22484827-8	2012	Sivelestat or edaravone treatment also attenuated the LPS-induced production of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor alpha (TNF-alpha) in rat lungs.	sivelestat	0-10	tumor necrosis factor	Rattus norvegicus	130-157	
22484827-8	2012	Sivelestat or edaravone treatment also attenuated the LPS-induced production of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor alpha (TNF-alpha) in rat lungs.	sivelestat	0-10	tumor necrosis factor	Rattus norvegicus	159-168