PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16533754-4	2006	SCF-induced activation of c-Jun N-terminal kinase was increased in Rabgef1-/- BMCMCs, but without corresponding significant increases in SCF-induced migration or adhesion.	bmcmcs	78-84	RAB guanine nucleotide exchange factor (GEF) 1	Mus musculus	67-74	
16533754-5	2006	SCF-mediated activation of the survival-enhancing kinase, Akt, also was increased in Rabgef1-/- BMCMCs, and these cells had a survival advantage over their +/+ counterparts in vitro.	bmcmcs	96-102	RAB guanine nucleotide exchange factor (GEF) 1	Mus musculus	85-92	
16533754-6	2006	Despite enhanced Ras activation in the absence of RabGEF1, SCF-induced proliferation was lower in Rabgef1-/- BMCMCs compared with their +/+ counterparts.	bmcmcs	109-115	RAB guanine nucleotide exchange factor (GEF) 1	Mus musculus	98-105	
16533754-7	2006	Finally, we found that c-Kit internalization was delayed in the absence of RabGEF1, probably reflecting a positive role for RabGEF1 in the regulation of endocytic events, and that infection of Rabgef1-/- BMCMCs with a wild-type RabGEF1 lentiviral construct normalized c-Kit internalization to the levels seen in +/+ BMCMCs.	bmcmcs	204-210	RAB guanine nucleotide exchange factor (GEF) 1	Mus musculus	193-200