PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8996188-0 1997 Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). rupatadine 0-10 patchy fur Mus musculus 73-99 8996188-0 1997 Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). rupatadine 0-10 patchy fur Mus musculus 101-104 8996188-10 1997 Overall, rupatadine combines histamine and PAF antagonist activities in vivo with high potency, the antihistamine properties being similar to or higher than those of loratadine, whereas rupatadine"s PAF antagonist effects were near those of WEB-2066. rupatadine 9-19 patchy fur Mus musculus 43-46 8996188-10 1997 Overall, rupatadine combines histamine and PAF antagonist activities in vivo with high potency, the antihistamine properties being similar to or higher than those of loratadine, whereas rupatadine"s PAF antagonist effects were near those of WEB-2066. rupatadine 186-196 patchy fur Mus musculus 199-202 8996188-11 1997 Rupatadine is therefore a good candidate for further development in the treatment of allergic and inflammatory conditions in which both PAF and histamine are implicated. rupatadine 0-10 patchy fur Mus musculus 136-139