PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21709429-1 2011 The present study was designed to investigate the effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (atorvastatin, pravastatin, simvastatin) on the pharmacokinetics of losartan and its active metabolite EXP-3174 in rats. losartan carboxylic acid 233-241 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 61-118