PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32326583-9	2020	Because temozolomide-resistant cells exhibited significantly increased Sp1 expression, we concluded that Sp1-mediated PERK/CHOP signaling inhibition protects glioblastoma against cancer therapies; hence, BA treatment targeting this pathway can be considered as an effective therapeutic strategy to overcome such chemoresistance and tumor relapse.	Temozolomide	8-20	DNA damage inducible transcript 3	Homo sapiens	123-127	
30649790-8	2020	And relapsed patients undergoing radiotherapy (RT) plus temozolomide chemotherapy after primary tumor removal induces C/EBP homologous protein (CHOP).	Temozolomide	56-68	DNA damage inducible transcript 3	Homo sapiens	118-142	
30649790-8	2020	And relapsed patients undergoing radiotherapy (RT) plus temozolomide chemotherapy after primary tumor removal induces C/EBP homologous protein (CHOP).	Temozolomide	56-68	DNA damage inducible transcript 3	Homo sapiens	144-148	
22745676-6	2012	TMZ treatment triggered ER stress with increased expression of GADD153 and GRP78 proteins, and deceased pro-caspase 12 protein.	Temozolomide	0-3	DNA damage inducible transcript 3	Homo sapiens	63-70	
27278525-0	2016	Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells.	Temozolomide	27-39	DNA damage inducible transcript 3	Homo sapiens	54-58	
27278525-14	2016	Knockdown of CHOP expression abolished the synergistic effect of FLT and TMZ in the C6 cells, which suggests that FLT may sensitize glioma cells to TMZ through activation of the CHOP-dependent apoptosis pathway.	Temozolomide	73-76	DNA damage inducible transcript 3	Homo sapiens	13-17	
27278525-14	2016	Knockdown of CHOP expression abolished the synergistic effect of FLT and TMZ in the C6 cells, which suggests that FLT may sensitize glioma cells to TMZ through activation of the CHOP-dependent apoptosis pathway.	Temozolomide	73-76	DNA damage inducible transcript 3	Homo sapiens	178-182	
23551302-10	2013	IGL-1 + MEL + TMZ induced a significant decrease in GRP78, pPERK, and CHOP activation after reperfusion.	Temozolomide	14-17	DNA damage inducible transcript 3	Homo sapiens	70-74